Prenatal vitamin d supplementation and child respiratory health: a randomised controlled trial.

Background: Observational studies suggest high prenatal vitamin D intake may be associated with reduced childhood wheezing. We examined the effect of prenatal vitamin D on childhood wheezing in an interventional study.

Methods: We randomised 180 pregnant women at 27 weeks gestation to either no vitamin D, 800 IU ergocalciferol daily until delivery or single oral bolus of 200,000 IU cholecalciferol, in an ethnically stratified, randomised controlled trial.

Functional cardiac MRI in preterm and term newborns.

Objective: To use cardiac MRI techniques to assess ventricular function and systemic perfusion in preterm and term newborns, to compare techniques to echocardiographic methods, and to obtain initial reference data.

Design: Observational magnetic resonance and echocardiographic imaging study.

Setting: Neonatal Unit, Queen Charlotte's and Chelsea Hospital, London, UK.