Publications by authors named "Stephen S Fitzsimons"
Sci Transl Med
November 2024
Article Synopsis
- Aberrant angiogenesis may contribute to cognitive decline and could serve as a therapeutic target for dementia prevention, though most prior studies have focused on animal models.
- This study evaluated the relationship between blood markers of angiogenesis and cognitive aging in a sample of 435 older adults, revealing significant associations that varied by sex, particularly in younger women compared to men.
- Results indicated that higher levels of certain angiogenic markers were linked to better executive function and less brain atrophy, suggesting the potential for targeting angiogenesis in addressing age-related cognitive impairment.
