Publications by authors named "Stephen R Shouldice"
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Synopsis of recent research by authors named "Stephen R Shouldice"
Stephen R Shouldice's research primarily focuses on the role of DsbA enzymes in bacterial virulence, particularly in Gram-negative pathogens such as Pseudomonas aeruginosa and Escherichia coli, highlighting their significance in oxidative protein folding and the biogenesis of virulence factors.
His studies advocate for anti-virulence strategies that target DsbA and similar oxidative folding catalysts, offering a promising alternative to traditional antibiotics in combating antibiotic resistance.
Shouldice's findings emphasize the conservation of DsbA enzymes across different bacteria, indicating a potential for developing broad-spectrum inhibitors that can mitigate virulence in various pathogenic organisms.
