Publications by authors named "Stephen Paul Fitzgerald"
Objectives: The sensitivities of the pituitary to thyroxine feedback, and the thyroid to thyrotropin stimulation determine the free thyroxine /thyrotropin feedback loop and can be described mathematically by two curves. It is not well understood how the two curves combine in a healthy population with normal thyroid function to express the individual balance points that are observed. This study was directed at this issue testing the possibilities of random combination and directed linkage between the two curves.
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- Researchers studied how Thyroid Stimulating Hormone (TSH) controls itself, which is called autoregulation.
- * They looked at how this self-control helps keep thyroid hormones, like free thyroxine, balanced in our bodies.
- * The findings suggest that TSH autoregulation helps reduce variations in hormone levels, making it easier for our bodies to maintain a healthy balance.
Context. Population studies of the distribution of T4/TSH set points suggest a more complex inverse relationship between T4 and TSH than that suggested by physiological studies. The reasons for the similarities and differences between the curves describing these relationships are unresolved.
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