Nonstandard do-not-resuscitate orders.

Purpose Of Review: Tattoos and medallions are examples of nonstandard do-not-resuscitate (DNR) orders that some people use to convey end-of-life wishes. These DNR orders are neither universally accepted nor understood for reasons discussed within this manuscript.

Recent Findings: Studies show both providers and patients confuse the meaning and implication of DNR orders.

Neuromonitoring with microdialysis in severe traumatic brain injury patients.

Background: Neuromonitoring with microdialysis has the potential for early detection of metabolic derangements associated with TBI.

Methods: 1,260 microdialysis samples from 12 TBI patients were analyzed for glucose, -lactate, pyruvate, lactate/pyruvate ratio (LPR), and lactate/glucose ratio (LGR). Analytes were correlated with the Glasgow Coma Scale (GCS) before surgery and with the Glasgow Outcome Scale (GOS) at the time of discharge.

Comparison of piperacillin/tazobactam and imipenem/cilastatin, both in combination with tobramycin, administered every 6 h for treatment of nosocomial pneumonia.

This randomized, double-blind, multicenter study compared the efficacy and safety of piperacillin/tazobactam (P/T) and imipenem/cilastatin (IMP), both in combination with an aminoglycoside, in hospitalized patients with acute nosocomial pneumonia (NP). Patients with acute NP, defined as pneumonia with symptoms > or = 48 h after admission or < or =7 days after hospital discharge, received infusions of 4 g/500 mg P/T or 500 mg/500 mg IMP every 6 h. Endpoints were clinical cure and microbiological response rates; pathogen eradication rates; length of hospital stay; hospital readmissions; and adverse events (AEs).

The development of a method to measure head acceleration and motion in high-impact crashes.

Objective: To establish a mechanism to obtain precise measurements of the accelerations of the head in the high-speed racing environment and during crash impacts. The long-term goal is to apply this system to the assessment of head injury in automobile racing drivers and then in participants in other helmeted sports.

Methods: A multidisciplinary team conceptualized, designed, and successfully tested a triaxial accelerometer system capable of measuring head acceleration and motion in high-impact crashes.

Physiological responses to high-speed, open-wheel racecar driving.

Unlabelled: High-speed auto racing has been demonstrated to produce accelerated heart rate (HR) during competition. However, it has not been determined whether the increase in HR was due to physical work efforts or a result of emotional stress.

Purpose: The purpose of this investigation was to examine the physiological responses associated with open-wheel automobile driving at competitive speeds.