Inflammation in osteoarthritis: the latest progress and ongoing challenges.

Purpose Of Review: The understanding of inflammation in osteoarthritis is rapidly evolving. This review highlights important basic science, mechanistic, and clinical findings since 2020 that underscore the current notion of osteoarthritis as an inflammatory disease.

Recent Findings: There exists a disconnect between clinical radiographic findings and patient symptoms in osteoarthritis.

JUE Insight: How much does COVID-19 increase with mobility? Evidence from New York and four other U.S. cities.

How effective are restrictions on mobility in limiting COVID-19 spread? Using zip code data across five U.S. cities, we estimate that total cases per capita decrease by 19% for every ten percentage point fall in mobility.