Development of a core outcome set for informed consent for therapy: An international key stakeholder consensus study.

Background: 300 million operations and procedures are performed annually across the world, all of which require a patient's informed consent. No standardised measure of the consent process exists in current clinical practice. We aimed to define a core outcome set for informed consent for therapy.

Activation of a cGAS-STING-mediated immune response predicts response to neoadjuvant chemotherapy in early breast cancer.

Background: The DNA-damage immune-response (DDIR) signature is an immune-driven gene expression signature retrospectively validated as predicting response to anthracycline-based therapy. This feasibility study prospectively evaluates the use of this assay to predict neoadjuvant chemotherapy response in early breast cancer.

Methods: This feasibility study assessed the integration of a novel biomarker into clinical workflows.

Resilience, burnout and coping mechanisms in UK doctors: a cross-sectional study.

Aims: This cross-sectional study aimed to assess resilience, professional quality of life and coping mechanisms in UK doctors. It also aimed to assess the impact of demographic variables, such as sex, grade and specialty on these factors.

Methods: During October and November 2018, medical doctors in the UK were eligible to complete an online survey made up of validated psychological instruments.

Resilience in medical doctors: a systematic review.

Introduction: Resilience can be difficult to conceptualise and little is known about resilience in medical doctors.

Aims: This systematic review discusses the existing literature on influences on resilience levels of medical doctors.

Methods: The bibliographic databases PubMed, MEDLINE, EMBASE and PsycINFO were searched from 2008 to November 2018 using keyword search terms resilience* AND ("medical physician*" OR doctor* OR surgeon* OR medical trainee* or clinician*).

Evaluating interventions for informed consent for surgery (ICONS): Protocol for the development of a core outcome set.

Background: The concept of informed consent is fundamental to medical practice. Shortcomings in the process can lead to patient complaints, litigation, unmet expectations and poor outcomes. Consent research has focused on developing tools to improve patient recall and understanding.

A study of the relationship between resilience, burnout and coping strategies in doctors.

Purpose Of The Study: The aim of this study was to measure resilience, coping and professional quality of life in doctors.

Study Design: A cross-sectional study using an online questionnaire in a single National Health Service trust, including both primary and secondary care doctors.

Results: 283 doctors were included.

Illness perception clusters at diagnosis predict psychological distress among women with breast cancer at 6 months post diagnosis.

Objective: This study aimed to examine the extent to which illness perceptions and coping strategies among women diagnosed with breast cancer explain psychological distress at diagnosis and at 6 months post diagnosis relative to demographic and illness-related variables.

Methods: Women were recruited to the study shortly after diagnosis. A total of 90 women completed study materials (Illness Perception Questionnaire-Revised, the Cancer Coping Questionnaire and the Hospital Anxiety and Depression Scale) at time 1.

The barrier method as a new tool to assist in career selection: covert observational study.

Objective: To determine if senior doctors' parking habits and skills are associated with clinical specialty and, if so, whether observation of junior doctors' parking could provide guidance in choice of specialty.

Design: Covert observational study.

Setting: Pass-card controlled consultants' car park (parking lot), December 2009.