Coordinating centers and multi-practice-based research network (PBRN) research.

Practice-based research networks (PBRNs) have emerged as laboratories in which to address important primary care challenges. In 2011, the Agency for Healthcare Research and Quality's PBRN database included more than 130 networks, most regional and some national, with member practices in every state. Regional networks may have certain advantages over national networks with respect to practice recruitment and project quality control because of closer relationships and shorter distances.

Monitoring and evaluation of programmes to prevent mother to child transmission of HIV in Africa.

Many countries are expanding the coverage of programmes to prevent mother to child transmission of HIV. Although the need is unquestionable, are concerned that without true measures of effectiveness we may not be making the best use of resources

Longitudinal antiretroviral adherence among adolescents infected with human immunodeficiency virus.

Objectives: To longitudinally follow a cohort of adolescents with human immunodeficiency virus (HIV) and to investigate long-term antiretroviral therapy adherence and factors associated with adherence.

Design, Setting, And Patients: Adolescents infected with HIV (N = 231; mean age, 18.4 years; 72.

Long-term mortality in the United States cohort of pituitary-derived growth hormone recipients.

Objective: Patients who received pituitary-derived growth hormone (GH) are at excess risk of mortality from Creutzfeldt-Jakob disease. We investigated whether they were at increased risk of death from other conditions, particularly preventable conditions.

Study Design: A cohort (N=6107) from known US pituitary-derived GH recipients (treated 1963-1985) was studied.

Barriers to HAART adherence among human immunodeficiency virus-infected adolescents.

Objectives: To investigate the barriers to highly active antiretrovial therapy (HAART) adherence among human immunodeficiency virus (HIV)-infected adolescents and to explore the association of barriers and nonadherence.

Design: Structured interviews were conducted to determine the barriers associated with adherence; principal component factor analysis was performed on scores of the 19 barrier variables.

Setting: Human immunodeficiency virus-infected adolescents were recruited from 13 US cities into the REACH (Reaching for Excellence in Adolescent Care and Health) Project, the first large-scale disease progression study of HIV-positive adolescents infected through sexual behavior or injection drug use.

Utility of cervicography in HIV-infected and uninfected adolescents.

Purpose: To compare cytology with cervicography in HIV-infected and uninfected adolescent females.

Methods: At the time of analysis, 334 girls aged 13-19 years from 13 U.S.

Human papillomavirus infection and abnormal cytology of the anus in HIV-infected and uninfected adolescents.

Objective: To examine the prevalence of and risk for anal human papillomavirus (HPV) infection and abnormal anal cytology in sexually active adolescents.

Design: Prevalence data from adolescents aged 13-18 years with and without HIV infection and with a history of high-risk sexual behavior.

Methods: HPV DNA was detected using amplification techniques.