Publications by authors named "Stephen E Follansbee"
The availability of 24 antiretroviral (ARV) drugs within six distinct drug classes has transformed HIV-1 infection (AIDS) into a treatable chronic disease. However, the ability of HIV-1 to develop resistance to multiple classes continues to present challenges to the treatment of many ARV treatment-experienced patients. In this case report, we describe the response to ibalizumab, an investigational CD4-binding monoclonal antibody (mAb), in a patient with advanced immunodeficiency and high-level five-class antiretroviral resistance.
View Article and Find Full Text PDFIncreased rates of appendicitis in HIV-infected men: 1991-2005.
J Acquir Immune Defic Syndr
September 2009
Article Synopsis
- The study aimed to compare surgical outcomes between HIV-infected and matched non-infected patients, focusing on complication rates and mortality after various surgeries over a 12-month period.
- Conducted at Kaiser Permanente in Northern California, the research involved 332 pairs of patients matched by demographics and surgical procedures, ensuring a comprehensive analysis of their postoperative results.
- Results showed that both groups had similar hospital stays and follow-up visits, indicating that HIV infection did not significantly impact surgical outcomes in the studied cohort.
Objective: To demonstrate relationships between plasma high-density lipoprotein (HDL) cholesterol and fat expansions in the fat redistribution syndrome.
Design: Patients who had significant buffalo humps or intra-abdominal fat (IAF) expansions were identified and their HDL levels were measured. Control patients were all those undergoing a single trial of antiretroviral treatment.