Are UK pharmacists ready for consultant-level practice? A cross-sectional survey of self-assessed development needs.

Objectives: The four nations of the United Kingdom (UK) have endorsed a new curriculum and credentialing process for consultant pharmacists. This study aimed to measure the self-reported consultant-level practice development needs of pharmacists across the UK.

Methods: The study was a cross-sectional electronic survey.

An Eye-Movement Analysis of Overt Visual Attention During Consecutive and Simultaneous Interpreting Modes in a Remotely Interpreted Investigative Interview.

Remote interpreting via video-link is increasingly being employed in investigative interviews chiefly due to its apparent increased accessibility and efficiency. However, risks of miscommunication have been shown to be magnified in remote interpreting and empirical research specifically on video-link remote interpreting is in its infancy which greatly limits the evidence base available to inform and direct evidence-based policy and best practice, particularly in the identification of the optimal mode(s) of interpreting to be used, namely consecutive and simultaneous. Consecutive interpreting refers to a process in which the interpreter transfers short segments of speech from one language into the other as each person speaks in managed turn-taking, while simultaneous interpreting refers to the transfer of natural speech from one language into another in a concurrent manner without the need for speakers to segment their speech.

Can omalizumab be used effectively to treat severe conjunctivitis in children with asthma? A case example and review of the literature.

A 14-year-old girl with poorly controlled asthma attended the difficult-to-treat asthma clinic for review. Although she has eosinophilia and significantly raised immunoglobulin E levels, she is not currently a candidate for omalizumab (Xolair). She also suffers from chronic urticaria, eosinophilic eosophagitis and severe conjunctivitis.

Daily stressors as antecedents, correlates, and consequences of alcohol and drug use and cravings in community-based offenders.

Justice-involved individuals with alcohol and drug use problems reoffend at higher rates than their nonusing counterparts, with alcohol and drug use serving as an important vector to recidivism. At the daily level, exposure to stressors may exacerbate problematic alcohol and drug use; at the individual level, prior treatment experiences may mitigate substance use as individuals adapt to and learn new coping mechanisms. We conducted a daily diary study using Interactive Voice Response technology over 14 consecutive days with 117 men on probation or parole participating in a community-based treatment program (n = 860 calls) and referred to medication-assisted treatment.

Medication-Assisted Treatment and Violent Outcomes in Community-Based Offenders with Alcohol and Drug Use Problems.

Objective: This study explored medication-assisted treatment (MAT), the combined use of medication and psychosocial treatment, as a strategy for reducing violent outcomes in community-based offenders. The primary aims were to: 1) examine associations between participant characteristics and treatment adherence; 2) examine associations between treatment adherence and substance use; 3) examine associations between treatment adherence and violent outcomes; and 4) determine whether associations between treatment adherence and violent outcomes may be attributable to reductions in substance use.

Method: Baseline interviews were completed with 129 male offenders in community-based treatment prior to their first MAT appointment.

Optical performance of an ultra-sensitive horn-coupled transition-edge-sensor bolometer with hemispherical backshort in the far infrared.

The next generation of far infrared space observatories will require extremely sensitive detectors that can be realized only by combining extremely low intrinsic noise with high optical efficiency. We have measured the broad-band optical response of ultra-sensitive transtion edge sensor (TES) bolometers (NEP≈2aW/Hz) in the 30-60-μm band where radiation is coupled to the detectors with a few-moded conical feedhorn and a hemispherical backshort. We show that these detectors have an optical efficiency of 60% (the ratio of the power detected by the TES bolometer to the total power propagating through the feedhorn).

Code status documentation in the outpatient electronic medical records of patients with metastatic cancer.

Background: Advanced care planning (ACP) is considered an essential component of medical care in the United States, especially in patients with incurable diseases. However, little is known about clinical practices in outpatient oncology settings related to discussing end-of-life care and documenting code status preferences in ambulatory medical records.

Objective: To assess the rate of documentation of code status in the electronic longitudinal medical records (LMR) of patients with metastatic cancer.

A poly(propylene glycol-co-fumaric acid) based bone graft extender for lumbar spinal fusion: in vivo assessment in a rabbit model.

Study Design: An animal model of posterolateral intertransverse process lumbar spinal fusion compared fusion rates amongst autologous bone (group 1), a porous, bioabsorbable, scaffold based on the biopolymer, poly(propylene glycol-co-fumaric acid) (PPF) (group 2), and a combination of autograft and the bioabsorbable scaffold (group 3).

Objectives: To evaluate the feasibility of augmenting spinal fusion with an osteoconductive and bioabsorbable scaffold as an alternative or as an adjunct, i.e.

An injectable porous poly(propylene glycol-co-fumaric acid) bone repair material as an adjunct for intramedullary fixation.

A bioresorbable bone repair material made from the unsaturated polyester poly(propylene glycol-co-fumaric acid), PPF, was investigated for its potential to act as an adjunct to alleviate the disadvantages associated with wire fixation. The PPF bone repair material is an injectable system that can be delivered to the intramedullary site and crosslinked in the presence of a hydroxylapatite filler and effervescent agents. To test the feasibility of using a bioabsorbable material as an adjunct in fracture fixation, femoral osteotomies were created in two groups of 10 Sprague-Dawley rats.

Enhanced peripheral nerve regeneration through a poled bioresorbable poly(lactic-co-glycolic acid) guidance channel.

In this study we investigated the effects of materials prepared with electrical poling on neurite outgrowth in vitro and nerve regeneration in vivo. Neuro-2a cells were seeded on poled and unpoled poly(lactic-co-glycolic) (PLGA) films and observed at time periods 24, 48 and 72 h post-seeding. The percentage of cells with neurites and the neurites per cell were quantified using light microscopy.

Dimensional stability of the alveolar ridge after implantation of a bioabsorbable bone graft substitute: a radiographic and histomorphometric study in rats.

This study evaluated reconstruction of the alveolar ridge after molar extraction in rats with bioabsorbable bone repair scaffolds. The material was prepared from the unsaturated polyester poly(propylene glycol-co-fumaric acid) (PPF), which may be cured in situ to form a porous scaffold. The intention is to use this material either as a stand-alone bone graft substitute or as an extender to autograft harvested from mandibular reconstruction sites.

Prediction of resorption rates for composite polylactide/hydroxylapatite internal fixation devices based on initial degradation profiles.

Mechanical and physicochemical outcomes were used to predict the resorption rate of polylactide-based internal fixation devices with and without incorporation of an osteoconductive buffer. Devices were degraded in vitro for 1 year. Addition of an osteoconductive buffer to a resorbable polymer internal fixation device controlled the rate of acid generation resulting from polymer hydrolysis.

Mechanical evaluation of a porous bone graft substitute based on poly(propylene glycol-co-fumaric acid).

A porous, resorbable polymer composite based on poly(propylene glycol-co-fumaric acid) (PPF) was mechanically evaluated in vitro for use as a bone graft substitute and fracture fixative. The test material created a dynamic system capable of initially providing mechanical integrity to bony voids and a degradative mechanism for ingrowth by native bone. The unsaturated polymer, PPF, was crosslinked in the presence of effervescent agents to yield a porous microstructure upon curing.