Publications by authors named "Stephen D Feren"
Article Synopsis
- The study aimed to assess how an SWS-enhancing drug, gaboxadol (GBX), affects behavioral, psychological, and physiological outcomes in people with restricted sleep.
- Conducted with 41 healthy adults over 4 nights of sleep restriction, the study found that those taking GBX experienced less sleepiness and fatigue compared to the placebo group, despite similar total sleep times.
- Although GBX improved subjective sleepiness and physiological responses, both groups performed similarly on cognitive tasks, indicating these tasks were less impacted by sleep restriction.
Study Objectives: To evaluate the impact of enhanced slow-wave sleep (SWS) on behavioral, psychological, and physiologic changes resulting from sleep restriction
Design: A double-blind, parallel-group, placebo-controlled design was used to compare tiagabine, 8 mg, (a SWS-enhancing drug) to placebo during 4 nights of sleep restriction (time in bed = 5 hours per night). Behavioral, psychological, and physiologic measures of the impact of sleep restriction were compared between groups at baseline, during sleep restriction, and following recovery sleep.
Setting: Two sleep research laboratories.