Publications by authors named "Stephen C Emencheta"

Many compounds and inorganic elements released from natural and anthropogenic origins contaminate the environment and are implicated in catastrophes involving most biologically driven ecological processes and public health. One such element is Mercury. Mercury exists in both inorganic elemental form and the more metabolically active molecular form e.

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Per- and polyfluoroalkyl substances (PFAS) are rampant, toxic contaminants from anthropogenic sources, called forever chemicals for their recalcitrance. Although banned in several parts of the world for public health implications, including liver, kidney, and testicular diseases, PFAS are abundant in water sources due to easy dispersion. With chemical properties resulting from strong hydrophobic bonds, they defile many physicochemical removal methods.

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Background: Multidrug resistance in Staphylococcus aureus continues to influence treatment complications in clinical settings globally. Multidrug-resistant-S. aureus (MDR-SA) is often genetically driven by resistance markers transferable in pathogenic strains.

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Bacteriophages (phages) are nano-sized viruses characterized by their inherent ability to live off bacteria. They utilize diverse mechanisms to absorb and gain entry into the bacterial cell wall via the release of viral genetic material, which uses the replication mechanisms of the host bacteria to produce and release daughter progeny virions that attack the surrounding host cells. They possess specific characteristics, including specificity for particular or closely related bacterial species.

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Due to the increasing limitations and negative impacts of the current options for preventing and managing diseases, including chemotherapeutic drugs and radiation, alternative therapies are needed, especially ones utilizing and maximizing natural products (NPs). NPs abound with diverse bioactive primary and secondary metabolites and compounds with therapeutic properties. Marine probiotics are beneficial microorganisms that inhabit marine environments and can benefit their hosts by improving health, growth, and disease resistance.

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This research work aimed at developing an edible biopolymeric microcapsular wrapping (EBMW) integrating lytic bacteriophage particles for , with potential application in poultry feed for biocontrol of that pathogen. This pathogen is known as one of the main microorganisms responsible for contamination in the food industry and in foodstuff. The current techniques for decontamination and pathogen control in the food industry can be very expensive, not very selective, and even outdated, such as the use of broad-spectrum antibiotics that end up selecting resistant bacteria.

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Background: Rapid emergence of multidrug resistant Staphylococcus aureus has resulted to difficulty in treatment of infections caused by such strains. The aim of this meta-analysis study was to determine the pooled prevalence of resistance of S. aureus to different antibiotics in Nigeria.

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Background: Regular evaluation of antimicrobials prescriptions is important for optimal use.

Objective: This study determined the prescription patterns, class and costs of antimicrobials in the adult out-patient pharmacy of a Teaching Hospital in Nigeria.

Methods: A 1-year retrospective study from 1st January to 31st December 2018.

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Background: Pharmaceutical products need to be of good quality and it is even more critical when it comes to life saving medicaments like infusions.

Objective: This research surveyed the quality fitness of some ciprofloxacin and metronidazole infusion samples marketed in South-eastern of Nigeria.

Methods: Using Official Compendial methods, microbiological quality, active pharmaceutical ingredients quantitation, pH and particle count tests were evaluated on eighty infusion bottles (from eight pharmaceutical companies) of each of the two drugs.

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