The vitamin B analog cobinamide ameliorates azide toxicity in cells, , and mice.

Context: The azide anion (N-) is highly toxic. It exists most commonly as sodium azide, which is used widely and is readily available, raising the potential for occupational incidents and use as a weapon of mass destruction. Azide-poisoned patients present with vomiting, seizures, hypotension, metabolic acidosis, and coma; death can occur.