Fire-retardant clothing-related dermatitis.

Background: Several laborers in a refinery unit undergoing a work over noted skin eruptions. Signs and symptoms included erythema, pruritus, scaling, and perifollicular inflammation on skin contacted by fire-retardant clothing (FRC).

Objective: The purposes of this report were to show a correlation between this rash outbreak and the use of FRC, to report the investigative results as to what aspect of the FRC most likely caused the dermatitis, and to present how this outbreak was ended.

Novel homozygous frameshift mutation of EVER1 gene in an epidermodysplasia verruciformis patient.

Epidermodysplasia verruciformis (EV) is a rare genetic skin disease with an autosomal recessive trait, and the patients have susceptibility to a specific group of human papillomavirus genotypes. Recently germline mutations in EVER1/2 genes have been detected in EV patients with different ethnic origins. In this study, we have applied PCR, single-stranded conformational polymorphism analysis, and sequencing as well as restriction fragment length polymorphism analysis for identifying potential mutation(s) of EVER genes in an EV patient and in the parents of Pakistani origin.

Long-term follow-up of basal cell carcinomas treated with perilesional interferon alfa 2b as monotherapy.

Background: Interferon alfa-2b (IFN) may be used to treat basal cell carcinoma (BCC) as an alternative to surgical or destructive methods.

Objective: The purpose of this study is to determine the long-term effectiveness of IFN treatment for BCC.

Methods: Fifty patients with 98 biopsy-proven primary superficial and nodular BCCs were treated perilesionally and intradermally with injections of IFN between 1985 and 1992.

Plantar wart treatment with combination imiquimod and salicylic acid pads.

Treatment of plantar warts is often difficult and may be painful, often employing destructive treatment modalities. We report the successful treatment of a patient with a large plantar wart using Imiquimod 5% cream under occlusion with a 40% salicylic acid pad. This combination treatment modality likely allows successful delivery of Imiquimod through the thick skin on the plantar surface.

Plantar wart treatment with combination imiquimod and salicylic acid pads.

Treatment of plantar warts is often difficult and may be painful, often employing destructive treatment modalities. We report the successful treatment of a patient with a large plantar wart using Imiquimod 5% cream under occlusion with a 40% salicylic acid pad. This combination treatment modality likely allows successful delivery of Imiquimod through the thick skin on the plantar surface.

Delayed staged closure with repeated directional suturing of cutaneous defects.

Background: Postsurgical wound management is traditionally a choice between intraoperative surgical repair or healing by secondary intention. We describe a technique that combines intraoperative and postoperative surgical repair with granulation.

Objective: Delayed closure with repeated directional suturing was evaluated as an alternative closure technique for large wounds.