Publications by authors named "Stephanie Ziant"
Background: Randomised controlled trials have shown that benralizumab, an anti-interleukin-5 receptor monoclonal antibody, reduces exacerbations and oral corticosteroid dose and improves asthma control and lung function in severe eosinophilic asthma. The aim of this study was to confirm results of randomised controlled trials in real life in a population of 73 patients with severe eosinophilic asthma treated with benralizumab for at least 12 months.
Methods: Patients underwent careful monitoring of asthma exacerbations, exhaled nitric oxide fraction, lung function, asthma control and quality of life questionnaire responses and sputum induction, and gave a blood sample at baseline, after 6 months and then every year.
Article Synopsis
- - Dyspnea is a type of respiratory discomfort often linked to heart or lung issues, but it can also stem from metabolic disorders.
- - The cause of dyspnea is complicated, arising from various brain interactions responding to internal sensations and pain.
- - When there's no obvious physical cause for dyspnea, known as dyspnea "sine materia," treatment focuses on behavioral therapy and breathing exercises, especially for those who are physically deconditioned.
Background: Staphylococcus aureus enterotoxins (SE) may act as superantigens and induce an intense T-cell activation, causing local production of polyclonal IgE and resultant eosinophil activation.
Objective: To assess whether asthma with sensitization to SE but not to common aeroallergens (AAs) displays different inflammatory characteristics.
Methods: We conducted a prospective study on a series of 110 consecutive patients with asthma recruited from the University Asthma Clinic of Liège.