Very low-dose radiation therapy for management of inflammatory myofibroblastic tumor of the lung.

Inflammatory myofibroblastic tumor (IMT) is an uncommon chest pathology. Treatment primarily focuses on surgical resection for diagnostic and therapeutic purposes. However, there are instances in which alternative therapies with steroids, chemotherapy, or radiation are necessary.

Purulent pericarditis, an unusual cause of cardiac arrest.

Purulent pericarditis is a rare infection of the pericardial space defined by the presence of gross pus or microscopic purulence. Here, we present a case of purulent pericarditis, leading to obstructive and septic shock. After prompt pericardial drainage, the patient experienced rapid improvement in symptoms.

Tissue distribution and clonal diversity of the T and B cell repertoire in type 1 diabetes.

The adaptive immune repertoire plays a critical role in type 1 diabetes (T1D) pathogenesis. However, efforts to characterize B cell and T cell receptor (TCR) profiles in T1D subjects have been largely limited to peripheral blood sampling and restricted to known antigens. To address this, we collected pancreatic draining lymph nodes (pLN), "irrelevant" nonpancreatic draining lymph nodes, peripheral blood mononuclear cells (PBMC), and splenocytes from T1D subjects ( = 18) and control donors ( = 9) as well as pancreatic islets from 1 T1D patient; from these tissues, we collected purified CD4 conventional T cells (Tconv), CD4 Treg, CD8 T cells, and B cells.