Publications by authors named "Stephanie Retsas"
Article Synopsis
- KCNV2-associated retinopathy is a genetic retinal disease, primarily affecting vision, and this study focuses on finding effective biomarkers for diagnosis and treatment.
- The research analyzed data from eight patients, examining visual acuity and various electroretinographic results, highlighting specific abnormalities in wave amplitudes and peak times.
- Three key biomarkers were identified for evaluating KCNV2 retinopathy: increased b-wave amplitude with light, delayed a-wave and b-wave peak times, and a high b:a wave ratio; these findings indicate the importance of early detection within the first 30 years of life for potential therapies.
Purpose: Mer tyrosine kinase-retinitis pigmentosa (RP) causes a primary defect in the retinal pigment epithelium, which subsequently affects rod and cone photoreceptors. The study aims to identify the most appropriate -RP biomarkers to measure disease progression for deciding the optimum therapeutic trial intervention time.
Materials And Methods: Patients' data from baseline (BL) and last follow-up (LFU) were reviewed.
Background: A great body of evidence suggests that there are retinal functional and structural changes that occur in Alzheimer's disease (AD). However, whether such changes are primary or secondary remains to be elucidated. We studied a range of retinal functional and structural parameters in association with AD- specific pathophysiological markers in the double transgenic APP/PS1 and control mice across age.
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