Publications by Stephanie M Sitterding

Publications by authors named "Stephanie M Sitterding"

Page 1 of 1

AlphaB-crystallin: a novel marker of invasive basal-like and metaplastic breast carcinomas.

Stephanie M Sitterding William R Wiseman Carol L Schiller Chunyan Luan Feng Chen

Ann Diagn Pathol

February 2008

Basal-like tumors are a newly recognized estrogen receptor (ER) negative and HER2 negative breast cancer subtype that express basal epithelial genes and are associated with poor survival. Metaplastic carcinomas are thought to belong within the basal-like group. We have recently demonstrated that the small heat shock protein alphaB-crystallin is commonly expressed in basal-like tumors and contributes to their aggressive phenotype.

View Article and Find Full Text PDF

- Stephanie M Sitterding's research primarily focuses on the molecular characteristics of aggressive breast cancer subtypes, particularly basal-like tumors and metaplastic carcinomas.
- In her 2008 study, she identified alphaB-crystallin as a novel marker for these cancer types, highlighting its common expression in basal-like tumors, which are typically estrogen receptor-negative and HER2-negative.
- The findings suggest that alphaB-crystallin may play a significant role in the aggressive behavior of these tumors, potentially offering insights for targeted therapies and improving the understanding of breast cancer prognosis.

Publications by authors named "Stephanie M Sitterding"

AlphaB-crystallin: a novel marker of invasive basal-like and metaplastic breast carcinomas.

Synopsis of recent research by authors named "Stephanie M Sitterding"