Publications by authors named "Stephanie L Nett"
Detection of SARS-CoV-2 IgG antibodies in dried blood spots.
Diagn Microbiol Infect Dis
September 2021
Article Synopsis
- - The COVID-19 pandemic prompted the creation of many serologic tests, leading researchers to validate dried blood spots (DBS) as a substitute for traditional blood collection methods.
- - The study found that antibodies could be effectively extracted from DBS samples stored properly, showing high agreement with standard serum tests for detecting anti-SARS-CoV-2 antibodies.
- - Using DBS for serologic testing is advantageous because it's low-cost, easy to collect, stable for shipping, and can help determine the antibody prevalence in large populations.
Purpose: The implementation of newborn screening for lysosomal disorders has uncovered overall poor specificity, psychosocial harm experienced by caregivers, and costly follow-up testing of false-positive cases. We report an informatics solution proven to minimize these issues.
Methods: The Kentucky Department for Public Health outsourced testing for mucopolysaccharidosis type I (MPS I) and Pompe disease, conditions recently added to the recommended uniform screening panel, plus Krabbe disease, which was added by legislative mandate.