Junctophilin-2 Regulates Mitochondrial Metabolism.

Right ventricular dysfunction (RVD) is a risk factor for mortality in multiple cardiovascular diseases, but approaches to combat RVD are lacking. Therapies used for left heart failure are largely ineffective in RVD, and thus the identification of molecules that augment RV function could improve outcomes in a wide-array of cardiac limitations. Junctophilin-2 (JPH2) is an essential protein that plays important roles in cardiomyocytes, including calcium handling/maintenance of t-tubule structure and gene transcription.

Information Avoidance in Consumer Choice: Do Avoidance Tendencies and Motives Vary by Age?

Prior research suggests that older adults seek less information in consumer choices than younger adults do. However, it remains unclear if intentional information avoidance plays a role in such effects. To test this possibility, we examined age differences in deliberate information avoidance in consumer decisions and explored a range of potential motives.

Age Differences in Media Consumption and Avoidance With Respect to COVID-19.

Background: Older versus younger adults are at greater risk from coronavirus disease 2019 (COVID-19), but descriptive data show they are less likely to seek out related information in the media, although underlying mechanisms remain unclear.

Method: A representative adult life-span sample (N = 500) completed a preregistered online study assessing changes in media consumption in response to the pandemic, self-reported and behavioral media avoidance, avoidance motives, and demographic, socioemotional, and cognitive covariates.

Results: Age was associated with reduced media consumption and higher behavioral media avoidance, but lower self-reported media avoidance and lower endorsement of specific avoidance motives.