Publications by authors named "Stephanie Knight"

Background: We observed rapid tumor progression following COVID-19 infection among patients with glioblastoma and sought to systematically characterize their disease course in a retrospective case-control study.

Methods: Using an institutional database, we retrospectively identified a series of COVID-19-positive glioblastoma cases and matched them by age and sex 1:2 to glioblastoma controls who had a negative COVID-19 test during their disease course. Demographic and clinical data were analyzed.

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Article Synopsis
  • Mr. A, a man with mental and physical disabilities, struggles with bipolar disorder, a spinal injury from a car accident, and alcohol addiction, leading to severe neuropsychiatric symptoms.
  • Despite treatment efforts, his agitation and mood swings improved, but his cognitive and speech impairments worsened irreversibly in a short time, causing confusion for the medical team.
  • Further investigations suggested that his neuropsychiatric issues stemmed from a combination of his bipolar disorder, alcohol-related dementia, and ongoing neurodegeneration, highlighting the complexity of treating such interrelated conditions.
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Aim: This paper reports on the publication of a joint statement on minimum standards for continence care in the UK.

Methods: A multidisciplinary working party were tasked with creating standards for both training and education in continence care, as well as explicit standards for a framework of service delivery. This was done through a process of extensive consultation with relevant professional bodies.

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We report the case of a 43 year old male with no prior psychiatric history with apparent tacrolimus-induced psychosis. Previous reports have identified other neurotoxic adverse effects due to tacrolimus, however, to our knowledge, there are few reports that describe psychosis induced by the immunosuppressant drug. Although psychosis may be a rare adverse effect, it can have significant impact on the long-term prognosis and treatment in transplant recipients.

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Aim: This paper reports on the recent publication and wide distribution of a joint statement on minimum standards for urodynamic practice in the UK.

Methods: A multidisciplinary working party were tasked with creating standards for both training and certification in urodynamics, as well as explicit standards for a framework of service delivery. This was done through a process of extensive consultation with relevant professional bodies.

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Beliefs have a significant effect on the health behaviors of individuals and educators; however, they can be difficult to change. The purpose of this study was to determine if exposing community health educators, specifically family and consumer sciences county extension educators, to a multicomponent professional development training on food irradiation could change their beliefs and behaviors. This study compared the food irradiation beliefs and educational programming of educators who participated in a professional development training with those who did not.

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The local lymph node assay (LLNA) is used to assess the skin sensitization potential of chemicals. In the standard assay, mice are treated topically on the dorsum of both ears with test substance for 3 days. Following 2 days of rest, the initiation of the hypersensitivity response is evaluated by injecting (3)H-thymidine into a tail vein, and then measuring the levels of radioisotope incorporated into the DNA of lymph node cells draining the ears.

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Objective: To develop an instrument to measure the food irradiation beliefs of community nutrition educators and to determine the influence of those beliefs on food irradiation educational outreach.

Design: Survey development, cross-sectional telephone survey.

Setting: Cooperative Extension Program.

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Phospholipidosis is the excessive accumulation of intracellular phospholipids in cell lysosomes. Drugs that induce this disease often share common physiochemical properties and are collectively classified as cationic amphiphilic drugs (CADs). Although the cause of phospholipidosis and morphologic appearance of affected lysosomes have been studied extensively, less is known about the physiologic effects of the condition.

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