Publications by authors named "Stephanie I Rizk"
Purpose Of Review: The aim of this study was to review the role of haemodynamic monitoring in the perioperative setting, highlighting who are the patients who most benefit, to describe the type of devices, to analyse the scientific evidence and to suggest algorithms of haemodynamic care in high-risk surgical patients.
Recent Findings: In the last 50 years, many advances have contributed to better understand cardiovascular physiology at bedside, and haemodynamic monitoring has moved from invasive methods to minimally invasive and noninvasive devices. Randomized clinical trials have shown benefits of perioperative haemodynamic therapy to improve outcomes in high-risk surgical patients.
Reverse cardiac remodeling may occur in some left ventricular assist device (LVAD) recipients. Although considered the standard therapy, surgical device explantation with repeat sternotomy might be undesirable or very high risk. On the other hand, there are few data reporting minimally invasive percutaneous LVAD deactivation.
View Article and Find Full Text PDFSARS-CoV-2, the causative agent of coronavirus disease 2019 (COVID-19), is responsible for the largest pandemic facing humanity since the Spanish flu pandemic in the early twentieth century. Since there is no specific antiviral treatment, optimized support is the most relevant factor in the patient's prognosis. In the hospital setting, the identification of high-risk patients for clinical deterioration is essential to ensure access to intensive treatment of severe conditions in a timely manner.
View Article and Find Full Text PDFArticle Synopsis
- - The COVID-19 pandemic prompted significant changes in healthcare routines and services to help control the virus and protect public health.
- - There is a heightened focus on managing patients in high-risk groups, specifically the elderly, those with cardiovascular diseases, and cancer patients.
- - Cardio-oncology has evolved to better meet the needs of these patients during the pandemic, prioritizing quality and safety in their care.
In face of the pandemic of the novel coronavirus disease 2019 (COVID-19), the management of patients with cardiovascular risk factors and/or disease is challenging. The cardiovascular complications evidenced in patients with COVID-19 derive from several mechanisms, ranging from direct viral injury to complications secondary to the inflammatory and thrombotic responses to the infection. The proper care of patients with COVID-19 requires special attention to the cardiovascular system aimed at better outcomes.
View Article and Find Full Text PDFBackground: In recent years, the field of cardio-oncology has grown worldwide, bringing benefits to cancer patients in terms of survival and quality of life. This study reports the experience of a pioneer cardio-oncology programme at University Cancer Hospital in Brazil over a period of 10 years, describing the clinical profile of patients and the clinical outcomes.
Methods: A retrospective study was conducted on a cohort of patients treated at the cardio-oncology programme from April 2009 to February 2019.
Objectives: Previous trials suggest that vasopressin may improve outcomes in patients with vasodilatory shock. The aim of this study was to evaluate whether vasopressin could be superior to norepinephrine to improve outcomes in cancer patients with septic shock.
Design: Single-center, randomized, double-blind clinical trial, and meta-analysis of randomized trials.
Background: Appropriate use of antimicrobials is essential to improve outcomes in sepsis. The aim of this study was to determine whether the use of a rapid molecular blood test-Septi (SF) reduces the antibiotic consumption through early de-escalation in patients with nosocomial sepsis compared with conventional blood cultures (BCs).
Methods: This was a prospective, randomized, superiority, controlled trial conducted at Sao Paulo Heart Institute in the period October 2012-May 2016.
Objective: To investigate the effects of the administration of 4% albumin on lactated Ringer's, when compared with lactated Ringer's alone, in the early phase of sepsis in cancer patients.
Design: Single-center, randomized, double-blind, controlled-parallel trial.
Setting: A tertiary care university cancer hospital.
Takotsubo syndrome: an overview of pathophysiology, diagnosis and treatment with emphasis on cancer patients.
Heart Fail Rev
November 2019
Article Synopsis
- Takotsubo syndrome is an important but often underdiagnosed condition that leads to temporary heart failure, usually triggered by stress.
- It is frequently linked with cancer, which can worsen patient outcomes, making early detection and treatment crucial.
- This manuscript aims to highlight the relationship between cancer and Takotsubo syndrome, summarizing evidence to help doctors manage affected patients more effectively.
Background: Perioperative goal-directed hemodynamic therapy (GDHT) has been advocated in high-risk patients undergoing noncardiac surgery to reduce postoperative morbidity and mortality. We hypothesized that using cardiac index (CI)-guided GDHT in the postoperative period for patients undergoing high-risk surgery for cancer treatment would reduce 30-day mortality and postoperative complications.
Methods: A randomized, parallel-group, superiority trial was performed in a tertiary oncology hospital.
Objectives: The aim of this study was to evaluate the efficacy of perioperative intra-aortic balloon pump use in high-risk cardiac surgery patients.
Design: A single-center randomized controlled trial and a meta-analysis of randomized controlled trials.
Setting: Heart Institute of São Paulo University.