Effectiveness of a fortified drink in improving B vitamin biomarkers in older adults: a controlled intervention trial.

Background: Older adults are reported to have sub-optimal B vitamin status; targeted food-based solutions may help to address this. The objectives of the OptiAge food intervention study were to develop and investigate the effectiveness of a B vitamin-fortified drink in improving B vitamin biomarkers in older Irish adults with a primary outcome of change in the B vitamin biomarker status.

Methods: A double-blinded randomised controlled trial was performed in parallel at University College Dublin and Ulster University.

Workflow Requirements for Cost-of-Care Conversations in Outpatient Settings Providing Oncology or Primary Care: A Qualitative, Human-Centered Design Study.

Background: Patients prefer to discuss costs in the clinical setting, but physicians and teams may be unprepared to incorporate cost discussions into existing workflows.

Objective: To understand and improve clinical workflows related to cost-of-care conversations.

Design: Qualitative human-centered design study.

Colorectal cancer survivors' challenges to returning to work: A qualitative study.

Objective: To assess the challenges and needs of colorectal cancer (CRC) survivors in maintaining employment and returning to work (RTW) from the perspectives of both CRC survivors and employers in the United States.

Methods: Semi-structured interviews with CRC survivors (n = 10) and employers (n = 4) were transcribed, coded and thematically analysed using NVivo 12 software.

Results: Workplace challenges for survivors included the following: inadequate availability of paid and unpaid leave, limited availability of workplace accommodations, and employers' lack of knowledge about CRC and the recovery process.

The effect of a randomized 12-week soy drink intervention on everyday mood in postmenopausal women.

Objective: Dietary soy may improve menopausal symptoms, and subsequently mediate mood. This novel study examines various doses of dietary soy drink on everyday mood stability and variability in postmenopausal women.

Methods: Community-dwelling women (n = 101), within 7 years postmenopause, consumed daily either a low (10 mg, n = 35), medium (35 mg, n = 37), or high (60 mg, n = 29) dose of isoflavones, for 12 weeks.

Consumption of a soy drink has no effect on cognitive function but may alleviate vasomotor symptoms in post-menopausal women; a randomised trial.

Purpose: Cognitive decline is commonly reported during the menopausal transition, with memory and attention being particularly affected. The aim of this study was to investigate the effects of a commercially available soy drink on cognitive function and menopausal symptoms in post-menopausal women.

Methods: 101 post-menopausal women, aged 44-63 years, were randomly assigned to consume a volume of soy drink providing a low (10 mg/day; control group), medium (35 mg/day), or high (60 mg/day) dose of isoflavones for 12 weeks.

Obesity, whole blood serotonin and sex differences in healthy volunteers.

Background: Obesity is a growing problem throughout Europe, where the rate has more than doubled over the past 20 years. Reduced circulating serotonin may contribute to the development of obesity. This study aimed to explore associations between whole blood (WB) serotonin concentrations and anthropometric measures.

The Greater Yellowstone Ecosystem: challenges for regional ecosystem management.

An adaptive management approach is necessary but not sufficient to address the long-term challenges of the Greater Yellowstone Ecosystem (GYE). Adaptive management, in turn, has its own particular challenges, of which we focus on two: science input, and stakeholder engagement. In order to frame our discussion and subsequent recommendations, we place the current management difficulties into their historical context, with special emphasis on the 1990 Vision document, which attempted a broad synthesis of management goals for the ecosystem.

Developing an optimal river typology for biological elements within the Water Framework Directive.

The Water Framework Directive requires a river classification based on environmental variables (a typology) to be created as a structure for reporting ecological status. A single permutation procedure, utilising the same variables repeatedly but with different categorical divisions, enabled both the choice of variables and the boundary divisions for these variables to be optimised simultaneously in the development of the typology. This, in addition to a data set which appropriately combined different biological elements, enabled a typology to be developed which was far more effective than a System A, CCA-derived or expert opinion-based typology in segregating communities.