Early Insights into Implementation of Universal Screening, Brief Intervention, and Referral to Treatment for Perinatal Substance Use.

Objectives: Perinatal substance use is a growing concern across the United States. Universal screening, brief intervention, and referral to treatment (SBIRT) is one systems-level approach to addressing perinatal substance use. The objective of this study is to assess early efforts to implement SBIRT in an outpatient obstetric clinic.

Effect of whole-body vibration exposures on physiological stresses: Mining heavy equipment applications.

The aim of this study was to employ validated biological markers to quantify the physiologic consequences of exposure to whole-body vibration (WBV) and evaluate the relative impact of mining vehicle operator vibration exposure on physiological responses as compared to vertical-axial dominant WBV. In a laboratory-based study with a repeated-measures design, we played actual field-measured floor vibration profiles into a 6-degree-of-freedom motion platform to create different realistic WBV exposures: 1) vertical-dominant vibration collected from long-haul trucks, 2) multi-axial vibration collected from mining heavy equipment vehicles, and 3) no vibration (control condition). Circulating biomarkers of interest were cortisol and catecholamines (epinephrine and norepinephrine) to assess physiological stress, interleukin-6 (IL-6) and tumor necrosis factor-α (TNFα) to test for inflammation, thiobarbituric acid reactive substances (TBARS) to measure oxidative stress, and myoglobin and plasma creatine kinase to assess muscle damage.