Publications by authors named "Stephanie Farrugia"

Article Synopsis
  • A 29-year-old woman experienced painful swelling and nodules on her legs after taking minocycline for acne for 3 years.
  • Biochemical tests revealed liver issues and positive antibodies indicative of an autoimmune response, leading to a skin biopsy that confirmed nodular vasculitis.
  • After stopping minocycline, her symptoms and liver function improved within 3 months, prompting caution about long-term minocycline use due to its potential to cause nodular vasculitis.
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Immune checkpoint inhibitors are increasingly being used to treat various malignancies. Despite their efficacy, they are known to potentially cause immune-related adverse effects, including dermatological manifestations. A rare cutaneous immune-related adverse effect is scleroderma, which has been reported to occur with anti-programmed cell death-1 (PD-1) agents such as pembrolizumab and nivolumab.

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Unlabelled: Thrombosis of the palmar digital veins is relatively rare, typically reported in women aged 35-65 years and most commonly occurring on the fourth digit. Clinical presentation varies and the lesion can present on the fingers or the palms of the hands. Diagnosis may be suspected clinically and confirmed on histology and radiologically.

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Unlabelled: A young man was treated in hospital for sepsis, disseminated intravascular coagulation and multi-organ failure. He was a regular intranasal cocaine user up to 1 day prior to symptom onset. Clinical examination revealed extensive retiform purpura affecting both his lower limbs.

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A 91-year-old Caucasian man on warfarin for atrial fibrillation presented in view of sudden-onset haemoptysis with fresh bleeding with clots immediately after having eaten a piping-hot traditional cheesecake (pastizz) and burning the soft-palate of his mouth. The haemoptysis had resolved by the time that the patient had arrived to hospital. On examination, a 2 cm by 2 cm dark red, solitary mass could be seen just anterior to the uvula.

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