Burden and determinants of multi-b/tsDMARD failure in psoriatic arthritis.

Objectives: Despite significant therapeutic advances in psoriatic arthritis (PsA), many patients do not achieve remission and cycle through multiple biologic (b)- or targeted synthetic (ts)- DMARDs. Identifying the underlying reasons for repetitive therapeutic failure remains a knowledge gap. Here we describe prescribing patterns and characteristics of PsA patients with multi-b/tsDMARD failure at the NYU Psoriatic Arthritis Center.

Racial and ethnic determinants of psoriatic arthritis phenotypes and disease activity.

Objective: Individuals of racially and ethnically diverse backgrounds are underrepresented in PsA research/clinical trials, despite evidence that their disease presentation, severity and course may be distinct. Here we aim to describe how race, ethnicity and other socioeconomic factors inform disease characteristics in PsA.

Methods: A total of 817 consecutive patients with PsA from a large, diverse metropolitan area were enrolled in an observational, longitudinal registry.