Publications by authors named "Stephanie E Novotny"
Identifying transdiagnostic correlates of response inhibition deficits is important for understanding risk for internalizing disorders. Little work has compared the relationships between internalizing symptoms and repetitive negative thinking (RNT) with response inhibition across non-emotional and emotional domains, and no work has compared these relationships for inhibition of socio-emotional relative to self-referential stimuli. Undergraduate students (N = 71, 18.
View Article and Find Full Text PDFObjective: Some studies have suggested alterations of structural brain asymmetry in attention-deficit/hyperactivity disorder (ADHD), but findings have been contradictory and based on small samples. Here, we performed the largest ever analysis of brain left-right asymmetry in ADHD, using 39 datasets of the ENIGMA consortium.
Methods: We analyzed asymmetry of subcortical and cerebral cortical structures in up to 1,933 people with ADHD and 1,829 unaffected controls.
Article Synopsis
- The study compares ADHD, ASD, and OCD using brain imaging data from over 5,000 healthy controls and numerous patients across different age groups, focusing on structural differences in the brain.
- No consistent differences were observed across all three disorders, with some specific findings like smaller hippocampal volumes in children with ADHD compared to OCD.
- The results highlight that while subtle differences exist between these disorders, the distinctions are most apparent in specific age groups, emphasizing ADHD's unique brain volume differences in younger individuals and ASD's cortical thickness variations in adults.
Objective: Neuroimaging studies show structural alterations of various brain regions in children and adults with attention deficit hyperactivity disorder (ADHD), although nonreplications are frequent. The authors sought to identify cortical characteristics related to ADHD using large-scale studies.
Methods: Cortical thickness and surface area (based on the Desikan-Killiany atlas) were compared between case subjects with ADHD (N=2,246) and control subjects (N=1,934) for children, adolescents, and adults separately in ENIGMA-ADHD, a consortium of 36 centers.