Mood and neuropsychological changes in women with midlife depression treated with escitalopram.

Objective: This study assessed mood and neuropsychological function in a population of middle-aged women with major depressive disorder treated with escitalopram.

Methods: Psychometric data measuring severity of depression were collected from 19 women and neuropsychological data were collected from 17 women aged between 45 and 65 years with a Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, diagnosis of major depression in a study in the Behavioral Neuroendocrinology Program at the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine. All women were treated with escitalopram in an open-label design.