Publications by authors named "Stephanie A Soderlund"
Article Synopsis
- Hyperpolarized xenon (Xe) MRI is a noninvasive imaging technique used to evaluate lung structure and function, particularly focusing on the effects of aging and diseases such as cystic fibrosis and asthma on alveolar size.
- Low signal-to-noise ratio (SNR) can negatively affect the accuracy of measurements like the apparent diffusion coefficient (ADC), leading to misleadingly low values, especially in diseased lung regions where ADCs can be abnormally high.
- The study applied a new denoising technique called Global Local Higher Order Singular Value Decomposition (GLHOSVD), which significantly improved image quality, enhanced SNR, and allowed for more accurate assessment of lung microstructure that was previously difficult to measure in high
Purpose: Hyperpolarized Xe MRI benefits from non-Cartesian acquisitions that sample k-space efficiently and rapidly. However, their reconstructions are complex and burdened by decay processes unique to hyperpolarized gas. Currently used gridded reconstructions are prone to artifacts caused by magnetization decay and are ill-suited for undersampling.
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