Successful treatment of 5-fluorouracil toxicosis with hemodialysis.

Objective: To describe the successful treatment of lethal dose 5-fluorouracil (5-FU) toxicosis using hemodialysis.

Case Summary: A 4-month-old intact female Golden Retriever was presented to the emergency department after ingesting 20 g of 5% 5-FU cream. The puppy developed refractory seizures and became comatose with uncontrolled tonic-clonic convulsions.

Pharmacokinetics and efficacy of trazodone following rectal administration of a single dose to healthy dogs.

Objective: To determine the pharmacokinetics and efficacy of trazodone following rectal administration of a single dose to healthy dogs.

Animals: 6 healthy adult dogs.

Procedures: Each dog received a single dose of trazodone (approx 8 mg/kg) per rectum.

Suspected Acute Respiratory Distress Syndrome Associated With the Use of Intravenous Lipid Emulsion Therapy in a Dog: A Case Report.

A 12-year-old male neutered Bichon Frise presented to the Emergency Department for stupor and bradycardia after ingestion of chocolate covered 450 mg (90 mg/kg) tetrahydrocannabinol. The patient was hospitalized for supportive care, IV fluid therapy and monitoring in the intensive care unit. During hospitalization the patient became comatose and bradypneic.

Presumptive intraperitoneal envenomation resulting in hemoperitoneum and acute abdominal pain in a dog.

Objective: To describe the clinical features, diagnostic findings, treatment, and outcome of a dog with acute abdominal pain and hemoperitoneum secondary to a presumptive intraperitoneal (IP) snakebite.

Case Summary: A 10-month-old castrated male mixed-breed dog was evaluated for suspected snake envenomation. The dog presented recumbent and tachycardic with signs of severe abdominal pain.

Evaluation of a point-of-care anticoagulant rodenticide test for dogs.

Objective: To evaluate a point-of-care anticoagulant rodenticide lateral flow analyzer for the detection of various rodenticide compounds.

Design: Prospective, laboratory study.

Setting: University teaching hospital.