Paraumbilical vein aneurysm: case report.

A 48-year-old female patient was found to have a paraumbilical vein saccular aneurysm, which is a rare consequence of portal hypertension. She presented with right upper quadrant pain and had a known diagnosis of alcoholic liver disease. This had progressed since her last admission.

PHIP-label: parahydrogen-induced polarization in propargylglycine-containing synthetic oligopeptides.

The unsaturated side chain of l-propargylglycine (Pra) was used to study parahydrogen-induced polarization (PHIP) in synthetic oligopeptides. For the first time PHIP-induced NMR signal enhancement was demonstrated using model peptides bearing various functional side chains.

Development of a functional cis-prolyl bond biomimetic and mechanistic implications for nickel superoxide dismutase.

During recent years several peptide-based Ni superoxide dismutase (NiSOD) models have been developed. These NiSOD models show an important structural difference compared to the native NiSOD enzyme, which could cause a completely different mechanism of superoxide dismutation. In the native enzyme the peptide bond between Leu4 and Pro5 is cis-configured, while the NiSOD models exhibit a trans-configured peptide bond between these two residues.