Tricuspid transcatheter edge-to-edge repair in a 72-year-old patient with a left ventricular assist device and prior mitral edge-to-edge repair: a case report.

Background: We report a case of a 72-year-old patient developing a significant tricuspid regurgitation (TR) 6 years after a left ventricular assist device (LVAD) implantation. The aim of this case is to demonstrate the feasibility of transcatheter edge-to-edge repair (TEER) of the tricuspid valve and the excellent clinical benefit in long-term follow-up in an LVAD patient.

Case Summary: Our patient presented with recurrent acute heart failure syndrome.

Anticoagulation versus antiplatelet therapy after percutaneous left atrial appendage closure-subanalysis from the multicenter LAARGE registry.

Purpose: Data regarding post-procedural antithrombotic therapy following percutaneous left atrial appendage (LAA) in real-world populations using various occluder systems is limited. In the present analysis, anticoagulation (AC) was compared against antiplatelet therapy (APT) using data from the real-world multi-center LAARGE study.

Methods: Patients following LAA closure enrolled in the LAARGE study were assigned to two groups depending on initial post-implantation antithrombotic regime consisting of either AC or APT.

Long-term transesophageal echocardiography follow-up after percutaneous left atrial appendage closure.

Background: Peri-device leaks and device thrombi are assumed to lead to ischemic events after percutaneous left atrial appendage occlusion (LAAO). While these device-related complications are well assessed until 12 months after LAAO, no data are available beyond this period.

Objective: The purpose of this study was to assess device-related complications beyond 12 months after LAAO.

Carotid artery stenting in clinical practice depending on patient age.

Background: The age-dependent outcome of carotid artery stenting (CAS) outside of randomized controlled trials is largely unknown. Therefore, we assessed acute and long-term results of CAS in a single-center real-world registry.

Methods: All symptomatic and asymptomatic patients who consecutively underwent CAS were enrolled into the present analysis.

Progressive dyspnea and signs of right heart dysfunction.

A 40-year-old woman was admitted due to dyspnea and fever. Transthoracic echocardiography revealed signs of right heart volume overload and vegetations on the tricuspid valve with insufficiency. Transesophageal echocardiography showed a sinus venosus defect (SVD) with significant left-to-right shunt.

Incidence and risk factors of embolized particles in carotid artery stenting and association with clinical outcome.

Background: One of the mechanisms for periprocedural neurologic events in carotid artery stenting (CAS) is catheter manipulation within the aorta and supraaortic arteries causing plaque embolization. Therefore, the present analysis sought to determine risk factors for embolic particle dimensions and their relationship with adverse clinical events after CAS.

Methods: Between 1999 and 2015 embolic protection devices (EPD) of a total of 944 CAS procedures were evaluated regarding the occurrence and size of captured particles.

Long-Term Outcomes of Carotid Artery Stenting in Clinical Practice.

Background: There is a lack of long-term data and data outside of controlled clinical trials in carotid artery stenting. Thus, we sought to evaluate the long-term effectiveness in stroke prevention by carotid artery stenting in a large number of patients in a real-world setting.

Methods And Results: The present work represents an all-comer registry with a strict, prospectively designed, follow-up protocol, including an independent pre- and postprocedural neurological assessment.

Learning Curve Assessment for Percutaneous Left Atrial Appendage Closure With the WATCHMAN Occluder.

Objectives: We sought to evaluate the effect of increasing experience with left atrial appendage (LAA) closure on short-term outcome.

Background: Data regarding the impact of the learning curve of LAA closure-particularly regarding technical aspects of the procedure-are lacking.

Methods: The present analysis represents first data from a single-center all-comer registry.

Stroke rates after carotid artery stenting depend on study-specific definitions.

Aims: There is no consensus definition for minor and major stroke in trials comparing CAS vs. CEA. In this study the patients of our large single-centre CAS registry suffering a procedure-related stroke were categorised as minor or major stroke according to study-specific definitions.

Predictors of minor versus major stroke during carotid artery stenting: results from the carotid artery stenting (CAS) registry of the Arbeitsgemeinschaft Leitende Kardiologische Krankenhausärzte (ALKK).

Background: Patient outcome, quality of life as well as health care costs differ between patients with minor versus major stroke during carotid artery stenting. Evaluation of predictors for both subtypes of strokes is of paramount importance.

Methods And Results: We analyzed data from the prospective, web-based German carotid artery stenting (CAS) registry.

The role of endovascular expertise in carotid artery stenting: results from the ALKK-CAS-Registry in 5,535 patients.

Purpose: Several scientific committees have proposed an accentuation of operator minimal requirements before accreditation for carotid artery stenting is granted. The current study aims to identify potential effects from increasing site experience on periprocedural safety and outcome of carotid artery stenting (CAS).

Methods: Between 1996 and December 2009, 5,535 procedures have been entered into the prospective, controlled ALKK-CAS-Registry.

Impact of aortic valve calcification on the outcome of transcatheter aortic valve implantation: results from the prospective multicenter German TAVI registry.

Objectives: Transcatheter aortic valve implantation (TAVI) is an emerging technology in patients with severe aortic stenosis.

Background: Whether the degree of aortic valve calcification impacts the outcome after TAVI has not been thoroughly evaluated.

Methods: We analyzed data from the prospective multicenter German TAVI registry, including 1,365 patients as of July 2010.

Painful congestion of the lower limbs and recurrent fever.

We describe a 45-year-old patient with massive pain and congestion in the lower limbs. In addition, he daily presented fever up to 39.5°C (103.

Patent foramen ovale closure with the SeptRx device initial experience with the first "In-Tunnel" device.

Objectives: The purpose of this study was to evaluate the safety and effectiveness of the SeptRx patent foramen ovale (PFO) closure device (SeptRx, Inc., Fremont, California).

Background: A PFO is a relatively common remnant of the fetal circulation that can be associated with cryptogenic stroke, transient ischemic attack, migraine, or decompression sickness.

Late complications of transcatheter closure of patent foramen ovale: new technology and new outcomes.

As a method to prevent recurrent paradoxical embolism and therefore cryptogenic stroke, catheter-based patent foramen ovale closure was first reported in 1992. Since then numerous different devices have been designed to prevent paradoxical embolism. The development of new devices has risen pretty rapidly.

New onset atrial fibrillation after patent foramen ovale closure.

Objectives: In this study, we evaluated the incidence of new onset atrial fibrillation (symptomatic or detected by routine ECG) after patent foramen ovale (PFO-) closure.

Background: Although atrial fibrillation is known to occur in some patients following patent foramen ovale closure, the incidence and the risk associated with each device is not well known.

Methods: We evaluated 1,349 consecutive patients who underwent PFO closure with an approved device and examined the incidence and risk factors associated with the development of atrial fibrillation.