Frequent Alzheimer's disease neuropathological change in patients with glioblastoma.

Background: The incidence of brain cancer and neurodegenerative diseases is increasing with a demographic shift towards aging populations. Biological parallels have been observed between glioblastoma and Alzheimer's disease (AD), which converge on accelerated brain aging. Here, we aimed to map the cooccurrence of AD neuropathological change (ADNC) in the tumor-adjacent cortex of patients with glioblastoma.

Augmented reality assistance for realization of incision planning and model-based analysis of the modified surface model.

In this paper an application for incision planning, AR-visualization of plan data and model-based analysis of the modified anatomical structure due to realization of the planned incision is presented. The developed algorithm detects modifications of the acquired surface model and generates a parameterized description of the wound.