Publications by authors named "Stephan Pinheiro Frankenfeld"
J Endocrinol
February 2014
Article Synopsis
- Anabolic-androgenic steroid abuse is on the rise, with doses significantly higher than therapeutic levels (10- to 100-fold), leading to various side effects, particularly on glucose metabolism during fasting.
- This study focused on the effects of high doses of nandrolone decanoate (DECA) on glucose regulation in male Wistar rats, comparing low therapeutic doses to high supraphysiological doses over an 8-week period.
- Results showed that high doses of DECA led to increased insulin levels but reduced glucose uptake in skeletal muscle, decreased fasting serum glucose, and impaired gluconeogenesis, indicating major disruptions in glucose metabolism.
