Binucleate germ cells in Caenorhabditis elegans are removed by physiological apoptosis.

Cell death plays a major role during C. elegans oogenesis, where over half of the oogenic germ cells die in a process termed physiological apoptosis. How germ cells are selected for physiological apoptosis, or instead become oocytes, is not understood.

Correction: Morphogenesis of the C. elegans Intestine Involves Axon Guidance Genes.

[This corrects the article DOI: 10.1371/journal.pgen.

Morphogenesis of the C. elegans Intestine Involves Axon Guidance Genes.

Genetic and molecular studies have provided considerable insight into how various tissue progenitors are specified in early embryogenesis, but much less is known about how those progenitors create three-dimensional tissues and organs. The C. elegans intestine provides a simple system for studying how a single progenitor, the E blastomere, builds an epithelial tube of 20 cells.