Implementation of an Electronic Approach to Psychosocial Screening in a Network of Pediatric Practices.

Objective: A network of 18 pediatric practice locations serving predominantly commercially insured patients implemented the electronic administration of the Pediatric Symptom Checklist-17 parent-report (PSC-17P) for all 5.50- to 17.99-year-old children seen for well child visits (WCVs) and wrote up the results as a quality improvement project.

Adsorption of Polyadenylic acid on graphene oxide: experiments and computer modeling.

In this work, we study the adsorption of poly(rA) on graphene oxide (GO) using AFM and UV absorption spectroscopies. A transformation of the homopolynucleotide structure on the GO surface is observed. It is found that an energetically favorable conformation of poly(rA) on GO is achieved after a considerable amount of time (days).

The effect of protonation of cytosine and adenine on their interactions with carbon nanotubes.

Placing electrical charges on nanomaterials is a means to extend their functional capabilities in nanoelectronics and sensoring applications. This paper explores the effect of charging nitrogen bases cytosine (Cyt) and adenine (Ade) via protonation on their noncovalent interaction with carbon nanotubes (CNT) using quantum chemical calculations performed at the M05-2X/6-31++G** level of theory alongside with a molecular graphics method. It is shown that the protonation of the bases causes threefold increase of the interaction energy in the CNT·Cyt·H and СNT·Ade·H complexes as compared to the CNT complexes formed with neutral bases.

Robot-assisted Laparoscopic Retroperitoneal Lymph Node Dissection for Testicular Cancer: Evolution of the Technique.

Background: Retroperitoneal lymph node dissection (RPLND) is an accepted staging and treatment option for nonseminomatous germ cell tumor. Robotic surgery offers technical advantages and is being increasingly used in urologic procedures.

Objective: To determine the feasibility and safety of robotic surgery for RPLND.

Noncovalent Interaction of Graphene with Heterocyclic Compounds: Benzene, Imidazole, Tetracene, and Imidazophenazines.

Noncovalent functionalization of graphene with organic molecules offers a direct route to multifunctional modification of this nanomaterial, leading to its various possible practical applications. In this work, the structures of hybrids formed by linear heterocyclic compounds such as imidazophenazine (F1) and its derivatives (F2-F4) with graphene and the corresponding interaction energies are studied by using the DFT method. Special attention is paid to the hybrids where the attached molecule is located along the graphene zigzag (GZZ ) and armchair (GAC ) directions.

Technique and outcomes of robot-assisted retroperitoneoscopic partial nephrectomy: a multicenter study.

Background: Robot-assisted retroperitoneoscopic partial nephrectomy (RARPN) may be used for posterior renal masses or with prior abdominal surgery; however, there is relatively less familiarity with RARPN.

Objective: To demonstrate RARPN technique and outcomes.

Design, Setting, And Participants: A retrospective multicenter study of 227 consecutive RARPNs was performed at the Swedish Medical Center, the University of Michigan, and the University of California, Los Angeles, from 2006 to 2013.

Effect of a low-fat fish oil diet on proinflammatory eicosanoids and cell-cycle progression score in men undergoing radical prostatectomy.

We previously reported that a 4- to 6-week low-fat fish oil (LFFO) diet did not affect serum insulin-like growth factor (IGF)-1 levels (primary outcome) but resulted in lower omega-6 to omega-3 fatty acid ratios in prostate tissue and lower prostate cancer proliferation (Ki67) as compared with a Western diet. In this post hoc analysis, the effect of the LFFO intervention on serum pro-inflammatory eicosanoids, leukotriene B4 (LTB4) and 15-S-hydroxyeicosatetraenoic acid [15(S)-HETE], and the cell-cycle progression (CCP) score were investigated. Serum fatty acids and eicosanoids were measured by gas chromatography and ELISA.

[The application of antiadhesive means in prevention of peritoneal commissures].

The article presents our experience with using antiadhesive means "Seprafilm", "Interceed" and "Adept" in patients with abdominal adhesive disease. "Seprafilm" was applied in 18 patients, among them 13 underwent laparoscopic and 5 open adhesiolysis. Liquid antiadhesive barrier "Adept" was used in 53 patients (in 33--laparoscopically and in 20--by laparotomy).

[An acute obturation in the small intestine caused by phytobezoar in adhesive disease of the abdomen].

Six cases of an acute obturation small bowel ileus observation, caused by phytobezoars, are presented. In 5 patients adhesive process in abdominal cavity was revealed after previously performed open operations. In 2 patients ileus was successfully managed using laparoscopic method--there were performed adhesiolysis, phytobezoar fragmentation, using Babcock forceps, and its conduction up to ileocaecal valve.

[Laparoscopic adhesiolysis in the treatment of acute adhesive obstruction of the small intestine].

The results of operative treatment of 59 patients, suffering an acute adhesive ileus of small intestine (ISI), are presented. In 28 patients obturation ileus was diagnosed intraoperatively and in 31 - the strangulation one. In 14 patients an early postoperative adhesive ISI was noted.

[The results of use of the antiadhesive seprafilm barrier in adhesive disease of abdomen].

The results of treatment of 16 patients with abdominal adhesive disease are presented. In the surveyed group there were 7 women and 9 men. The average age of patients was 47,7 ± 14,0 (23-71).

[Treatment of early postoperative adhesive small bowel obstruction].

The results of treatment of 22 patients (12 men, 10 women) with acute early postoperative adhesive small bowel obstruction are presented. Obturation was detected in 16, strangulation - in 6 cases. In 12 patients obstruction was solved laparoscopically, in 8 patients laparotomy was performed, in two cases conversion was done.

Raman spectroscopy study and first-principles calculations of the interaction between nucleic acid bases and carbon nanotubes.

In this work, we have used Raman spectroscopy and quantum chemical methods (MP2 and DFT) to study the interactions between nucleic acid bases (NABs) and single-walled carbon nanotubes (SWCNT). We found that the appearance of the interaction between the nanotubes and the NABs is accompanied by a spectral shift of the high-frequency component of the SWCNT G band in the Raman spectrum to a lower frequency region. The value of this shift varies from 0.

Prostate cancer severity among low income, uninsured men.

Purpose: The proportion of American men with organ confined, low risk prostate cancer has increased significantly during the last 2 decades. Whether this trend also applies to men at the extremes of socioeconomic disadvantage remains unknown. Therefore, we evaluated trends in prostate cancer severity in an ethnically diverse cohort of low income, uninsured men served by a state funded public health program in California.

Racial disparities in access to care for men in a public assistance program for prostate cancer.

California's IMPACT program provides all its enrollees with health insurance and social service resources. We hypothesized that racial/ethnic disparities in access to care might be attenuated among men served by this program. Our objective was to evaluate racial/ethnic differences in health services utilization and patient-reported health care outcomes among disadvantaged men in a prostate cancer public-assistance program, and to identify modifiable factors that might explain persistent disparities in this health care setting.

SWNT-DNA and SWNT-polyC hybrids: AFM study and computer modeling.

Hybrids of carbon single-walled nanotubes (SWNT) with fragmented single or double-stranded DNA (fss- or fds-DNA) or polyC were studied by Atom Force Microscopy (AFM) and computer modeling. It was found that fragments of the polymer wrap in several layers around the nanotube, forming a strand-like spindle. In contrast to the fss-DNA, the fds-DNA also forms compact structures near the tube surface due to the formation of self-assembly structures consisting of a few DNA fragments.

Medication reconciliation: Harvard Pilgrim Health Care's approach to improving outpatient medication safety.

Hospitals and long-term care facilities have been addressing the issue of patient safety for some time. As a result of the increasing number of outpatient medication errors leading to adverse drug events (ADEs), interest in preventing outpatient medication errors has increased. Research indicates that the rate of outpatient ADEs may be about four times as high as that reported in hospital studies and that more than one third of these events are preventable (Gandhi et al.

Positive margins in laparoscopic partial nephrectomy in 855 cases: a multi-institutional survey from the United States and Europe.

Purpose: Open partial nephrectomy has emerged as the standard of care in the management of renal tumors smaller than 4 cm. While laparoscopic radical nephrectomy has been shown to be comparable to open radical nephrectomy with respect to long-term outcomes, important questions remain unanswered regarding the oncological efficacy of laparoscopic partial nephrectomy. We examined the practice patterns and pathological outcomes following laparoscopic partial nephrectomy.

[Natural killer cell immunodeficiency and herpesvirus infection in tuberculosis].

An inverse correlation was shown between the activity of natural killer cells (NKC) and the activated infection to herpes simplex virus (HSV)-1 and HSV-2. There was a significant reduction in CD56+ cells in patients who had a history of a concomitance of pulmonary tuberculosis and HSV-2 infection. In patients with tuberculosis, the decreased activity of NKC may activate HSV-1 infection, with its further involvement as an independent factor in the development of meningoencephalitis.

Use of haemostatic agents and glues during laparoscopic partial nephrectomy: a multi-institutional survey from the United States and Europe of 1347 cases.

Objectives: Laparoscopic partial nephrectomy (LPN) is a technically challenging procedure for the management of renal tumours. Major complications of LPN include bleeding and urine leakage. Haemostatic agents (HAs) and/or glues may reduce haemorrhage and urine leakage.

IR spectra of photopolymerized C60 films. Experimental and density functional theory study.

IR spectra of photopolymerized fullerene films obtained by simultaneous deposition and UV irradiation were measured in the range of 1500-450 cm(-1). The degree of the polymerization of the C60 films was estimated to be about 95%. To assist the assignment of the experimental IR spectra of the films, quantum chemical calculations of the equilibrium structures of the C60 dimers and trimers were performed at the DFT(B3LYP)/3-21G level of theory.

[The role of herpes simplex of type 1 infection in the development of tuberculous meningoencephalitis].

Cases of tuberculous meningoencephalitis in Armenia and a role of the activation of human herpes virus-1 (HHV-1) infection have been investigated. HHV-1 can be an independent factor in the development of meningoencephalitis and a cofactor that produces cellular immunodeficiency in patients with atypical tuberculous meningoencephalitis.

Evaluation of the reduction of imidazophenazine dye derivatives under fast-atom-bombardment mass-spectrometric conditions.

Satellite [M + 2](+*) and [M + 3](+) peaks accompanying the common peak of the protonated molecule [M + H](+) that are known to indicate the occurrence of a reduction process were observed in the fast atom bombardment (FAB) mass spectra of imidazophenazine dye derivatives in glycerol matrix. The distribution of the abundances in the [M + nH](+) peak group varied noticeably for different derivatives. This indicated different levels of the reduction depending on the different structure variations of the studied molecules.

Isotope effects in dipole-bound anions of acetone.

Precision measurements using the Rydberg charge-exchange and electric field-detachment methods find that the dipole-bound electron affinity (EA) of acetone (C3H6O) is 55+/-10 mueV greater than for deuterated acetone (C3D6O). The result agrees well with a theoretical prediction obtained with high-level electronic-structure and anharmonic vibrational calculations. The dipole moments calculated for the vibrationally averaged structures of C3H6O and C3D6O show that the isotope effect (2% reduction) on the EA of acetone is mainly due to a slight reduction (0.