The Resistance of to Oxidative, Genotoxic, Proteotoxic, Osmotic Stress, Infection, and Starvation Depends on Age According to the Stress Factor.

We studied how aging affects the ability of to tolerate various types of stress factors. Data were obtained on the resistance of to oxidative and genotoxic (separately paraquat, Fe, Cu, and Zn ions), proteotoxic (hyperthermia, Cd ions), and osmotic (NaCl) stresses, starvation, and infection with the pathological fungus at different ages. In all cases, we observed a strong negative correlation between age and stress tolerance.