Publications by authors named "Sten Isaksson"

The purpose of the study was to evaluate histologically, whether vertical bone augmentation can be achieved using a hollow ceramic space maintaining device in a rabbit calvaria model. Furthermore, the chemistry of microporous hydroxyapatite and zirconia were tested to determine which of these two ceramics are most suitable for guided bone generation. 24 hollow domes in two different ceramic materials were placed subperiosteal on rabbit skull bone.

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Objective: The purpose of this study was to evaluate 3-dimensionally whether vertical bone augmentation can be achieved using a hollow hydroxyapatite space-maintaining device in a rabbit calvarial model. Furthermore, different inner surface topographies, different permeabilities, and different porosities of the ceramic were tested to determine the optimal conditions for bone regeneration.

Study Design: A total of 48 hollow domes made of hydroxyapatite in 4 different designs were placed subperiosteally on rabbit skull bone.

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Background: There is lack of evidence on long-term success of short dental implants in reduced alveolar bone.

Purpose: In this prospective 5-year study, survival and marginal bone loss of 4-mm implants, which supported fixed dental prostheses (FDPs) in severely resorbed posterior mandibles, were evaluated.

Material And Methods: In 28 patients, evaluation of 86 osseointegrated 4-mm-long implants, which supported a 3- or a 4-unit FDP by crown splinting without the use of pontics or cantilevers, was performed over a 5-year period.

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Purpose: To compare three different lateral sinus elevation procedures concerning new bone formation by using micro-computed tomography (micro-CT) of retrieved implants.

Materials And Methods: Twenty-four consecutive partially dentate patients with a mean age of 64 years were included in the study and provided with 30 sinus elevation procedures. Three procedures for lateral sinus elevation were used: lateral sinus elevation with replacement of bone window and without bone graft (BW), lateral sinus elevation and covering osteotomy site with a collagen membrane and without bone graft (CM), and lateral sinus elevation with autogenous bone graft (ABG).

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Purpose: To evaluate the outcome of intraoral soft tissue expansion by measuring the profile change using objective 3D metering equipment and to evaluate localized bone grafting after soft tissue expansion with regard to gain of bone and complications.

Materials And Methods: Using a prospective study design, we asked patients with an osseous and soft tissue defect on the buccal aspect of the alveolar process to participate in this study. In 10 patients (experimental group) a self-inflatable soft tissue expander was placed under the periosteum.

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Purpose: To investigate the periapical tissue response of 4 different retrograde root-filling materials, ie, intermediate restorative material, thermoplasticized gutta-percha, reinforced zinc oxide cement (Super-EBA), and mineral trioxide aggregate (MTA), in conjunction with an ultrasonic root-end preparation technique in an animal model.

Materials And Methods: Vital roots of the third and fourth right mandibular premolars in 6 healthy mongrel dogs were apicectomized and sealed with 1 of the materials using a standardized surgical procedure. After 120 days, the animals were sacrificed and the specimens were analyzed radiologically, histologically, and scanning electron microscopically.

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Objectives: To evaluate the space-maintaining capacity of titanium mesh covered by a collagen membrane after soft tissue expansion on the lateral border of the mandible in rabbits, and to assess bone quantity and quality using autogenous particulate bone or bone-substitute (Bio-Oss(®) ), and if soft tissue ingrowth can be avoided by covering the mesh with a collagen membrane.

Material And Methods: In 11 rabbits, a self-inflatable soft tissue expander was placed under the lateral mandibular periosteum via an extra-oral approach. After 2 weeks, the expanders were removed and a particulated onlay bone graft and deproteinized bovine bone mineral (DBBM) (Bio-Oss(®) ) were placed in the expanded area and covered by a titanium mesh.

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Background: Reduced alveolar bone volume complicates implant dentistry.

Purpose: In this prospective multicenter study, a new, 4-mm long Straumann SLActive implant (Ø 4.1 mm) supporting a fixed dental prosthesis (FDP) in the severely resorbed posterior mandible was evaluated for two years.

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Implants integrated into bone have revolutionised the retention of total nasal prostheses. However, it may be difficult to identify available sites for placement of the implant after excision. In addition, it is ideal to minimise wide bony exposure after radiotherapy to avoid compromising the blood supply.

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Objective: This study evaluated the treatment outcome after periapical surgery with the use of 2 different retrograde root-filling materials and the influence of 3 pre- and perioperative variables on the periapical healing.

Study Design: Two hundred six teeth in 164 patients were randomly allocated to receive either IRM or Super-EBA as a retrograde root-end seal. The teeth were reviewed 12 months after surgery.

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Background: Survival rates of implants placed in transalveolar sinus floor augmentation sites are comparable with those placed in non-augmented sites. Flapless implant surgery can minimize postoperative morbidity, alveolar bone resorption and crestal bone loss. The use of cone beam computerized tomography (CBCT) provides 3D presentations with reduced dose exposure.

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Objectives: To evaluate the space-maintaining capacity of a titanium mesh or a bioresorbable mesh after periosteal expansion and to assess bone formation under a titanium mesh or a bioresorbable mesh on the lateral border of the mandible by qualitative and quantitative histological analysis.

Material And Methods: In 13 rabbits, a self-inflatable soft tissue expander was placed intraorally, bilaterally under the mandibular periosteum via an extra oral approach. After 2 weeks, the expanders were removed and a particulated onlay bone graft was placed and covered by a titanium mesh or a bioresorbable mesh.

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Background: The mere lifting of the maxillary sinus membrane by implants protruding into the sinus cavity allows the establishment of a void space for blood clot and new bone formation.

Purpose: To evaluate bone formation by using a spherical, hollow, and perforated hydroxyapatite space-maintaining device (HSMD) in a two-stage sinus lift procedure where residual alveolar bone height was ≤2 mm.

Material And Methods: Spherical, hollow, and perforated HSMDs with a diameter of 12 mm were manufactured for this pilot study.

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Purpose: The aim of this study was to prospectively evaluate the status of implants, marginal bone loss, and outcome of maxillary sinus floor augmentation in patients undergoing maxillary sinus lift and simultaneous implant placement with the use of bone grafts harvested adjacent to the actual surgical site.

Materials And Methods: Patients in need of maxillary sinus floor augmentation to enable implant placement were enrolled in 2 different groups. In group A, a "bone trap" was used to harvest bone debris during implant preparation with additional bone collected by further drilling adjacent to the implant sites.

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Objective: The aim of this study was to evaluate the healing outcome after periapical surgery with an ultrasonic cleaning technique in conjunction with the use of either of 2 different retrograde root-filling materials in teeth with apical periodontitis.

Study Design: One hundred sixty teeth in 139 consecutive patients were randomly allocated into 2 groups receiving either IRM or thermoplasticized gutta-percha (GP) with AH Plus sealer as a retrograde root-end seal. The patients were reviewed 12 months after surgery.

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Aim: The aim of this study was to investigate oral health and oral implant status in a group of edentulous patients receiving long-term residential or nursing care (LTC), all of whom had implant-supported fixed or removable dental prostheses.

Material And Methods: A dental examination was performed on a total of 3310 patients receiving LTC and from this population 35 edentulous patients in whom dental implants had been placed formed the cohort for this study. All examinations were performed by a specialist in hospital dentistry and took place in the patients' own home environment.

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We aimed to evaluate a new technique for intraoral expansion of soft tissue with a self-inflatable expander in rabbits. We placed a self-inflatable soft tissue expander bilaterally in eight rabbits under the periosteum of the mandible through an extraoral approach. The expander was left to self-inflate for two weeks, after which the animals were killed and specimens collected for histological examination.

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Purpose: This prospective study followed 61 patients who were partially dentulous and considered to have insufficient bone volume for routine implant treatment and consequently underwent sinus inlay bone grafting.

Patients And Methods: The patients were treated with maxillary sinus floor augmentation with particulated autogenous bone from the mandibular ramus/corpus. After a healing period, dental implants (n = 180) were installed.

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Purpose: The purpose of the present study was to compare lag screw fixation versus miniplates with monocortical screw technique with respect to the amount of transverse displacement of the proximal segment after bilateral sagittal osteotomy (BSO) for mandibular advancement surgery.

Patients And Methods: We conducted a multicenter, retrospective investigation of 82 patients who underwent a mandibular advancement with BSO and rigid internal fixation. Forty-five patients from Denmark and Sweden, the miniplate fixation group, received a rigid fixation consisting of miniplates with monocortical screws.

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Background: The use of a submerged implant system in a nonsubmerged surgical procedure has been reported to have promising results. At the time this study was initiated, no prospective, comparative studies with randomization between submerged and nonsubmerged surgical techniques had been published.

Purpose: To evaluate the submerged and nonsubmerged surgical techniques when treating mandibular edentulism using a submerged implant system, with regard to implant survival and complications.

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Purpose: The aim of this study was to analyze the survival rate of endosseous implants placed in the partially dentate maxilla treated with sinus inlay block bone grafts.

Materials And Methods: Seventeen patients were subjected to bone augmentation procedures prior to or in conjunction with implant placement. Bone volumes were regarded as insufficient for implant treatment unless a bone grafting procedure was performed.

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Purpose: The purpose of this clinical investigation was to evaluate the treatment outcome with zygoma implants with regard to implant survival, patient satisfaction, and function of prosthesis replacement after 3 years.

Patients And Methods: The treatment outcome of 76 patients treated with 145 zygoma fixtures at 16 centers was evaluated with regard to implant survival. Status of peri-implant mucosa and amount of plaque were registered annually.

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Purpose: The aim of this prospective study was to evaluate the current method of periapical surgery at the Maxillofacial Unit, Halmstad Hospital, which included ultrasonic root-end preparation and the use of intermediate restorative material as a root-end filling material.

Patients And Methods: Fifty-five consecutive patients with a total of 56 treated teeth, within the close vicinity of the hospital, were included in the study during a period of 10 months in 2002. Teeth with advanced periodontal bone loss or presence of root fractures were excluded from the study.

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Equipment from GFMesstechnik, Germany, for three-dimensional (3D) measurements of topography alterations was tested in an intra oral situation. A patient with previous loss of tooth 21 due to trauma planned for local bone grafting procedure together with a titanium mesh and later implant insertion was signed as a trial. Pre- and postoperative measurements of the buccal contour in maxillary anterior region were performed with the 3D equipment and the pictures were evaluated in a software programme.

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Background: The use of a specially designed implant to be anchored in the zygomatic body has been proposed as an alternative to bone grafting in the prosthetic rehabilitation of the severely resorbed maxilla. However, few studies have evaluated the long-term stability and soft tissue conditions of zygomatic implants.

Purpose: The aim of this retrospective study was to evaluate the clinical performance of zygomatic implants when used for prosthetic reconstruction of atrophic maxillae.

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