An observational study of pregnancy and post-partum outcomes in women with prolactinoma treated with dopamine agonists.

Background: In women with prolactinoma medical treatment with dopamine agonists (DA) can restore fertility. A number of studies have established the safety of DA during pregnancy and the impact of pregnancy and lactation on remission of prolactinoma. However, the total number of reported cases remains modest and further evidence is needed.

Discordant Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome in identical twins - a case report and implications for reproduction in MRKH women.

Infertility has previously been considered as an inevitable consequence of Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome. With modern assisted reproductive technology (ART) techniques becoming increasingly accessible, MRKH women have the opportunity for their own genetic offspring. The availability of such technology, however, increases the importance of understanding the aetiology of this complex condition.

Polycystic ovary syndrome and depression in New Zealand adolescents.

Objective: To determine whether adolescents with polycystic ovary syndrome (PCOS) are more depressed than adolescent girls in the community and to examine factors associated with depression.

Design: An observational study comparing clinical and community samples.

Setting: Two specialist reproductive endocrine clinics in Auckland, New Zealand.

Temporal changes in insulin-like growth factors I and II and in insulin-like growth factor binding proteins 1, 2, and 3 in human milk.

Aim: To evaluate the postpartum time course of changes in insulin-like growth factors (IGFs) and their binding proteins (IGFBPs).

Methods: Breast milk IGF-I and IGF-II and IGFBP-1, IGFBP-2, and IGFBP-3 levels were determined in 23 women with babies born at term, from day 4 until up to 9 months after birth.

Results: The IGFBP-3 levels were highest from day 4 to day 6 and then decreased by days 10-12.

LH levels in women with polycystic ovarian syndrome: have modern assays made them irrelevant?

Objective: To determine whether using newer monoclonal rather than polyclonal assays for measuring luteinising hormone (LH) alters the predictive value of LH and LH/follicle-stimulating hormone (FSH) ratios for polycystic ovarian syndrome.

Design: Prospective cohort study.

Setting: Fertility and Reproductive Endocrinology Clinic within a New Zealand Teaching hospital.

Factors associated with pregnancy or miscarriage after clomiphene therapy in WHO group II anovulatory women.

Objectives: The present study was designed to determine whether clinical and endocrine characteristics assessed on initial screening of normogonadotropic oligo/amenorrhoeic infertile patients could predict ovulation and then conception and successful live birth or miscarriage.

Study Design: Retrospective cohort study

Setting: Outpatient clinic.

Population: Eighty-two consecutive women receiving clomiphene citrate (CC) therapy from 1993 to 1998.