Publications by authors named "Stella L Papadopoulou"

Objectives: To determine the diagnostic performance of CT coronary angiography (CTCA) in detecting and excluding left main (LM) and/or three-vessel CAD ("high-risk" CAD) in symptomatic patients and to compare its discriminatory value with the Duke risk score and calcium score.

Materials And Methods: Between 2004 and 2011, a total of 1,159 symptomatic patients (61 ± 11 years, 31 % women) with stable angina, without prior revascularisation underwent both invasive coronary angiography (ICA) and CTCA. All patients gave written informed consent for the additional CTCA.

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Objective: To investigate the value of the calcium score (CaSc) plus clinical evaluation to restrict referral for CT coronary angiography (CTCA) by reducing the number of patients with an intermediate probability of coronary artery disease (CAD).

Methods: We retrospectively included 1,975 symptomatic stable patients who underwent clinical evaluation and CaSc calculation and CTCA or invasive coronary coronary angiography (ICA). The outcome was obstructive CAD (≥50 % diameter narrowing) assessed by ICA or CTCA in the absence of ICA.

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Article Synopsis
  • This study compared the diagnostic performance and radiation exposure of different CT coronary angiography (CTCA) protocols to detect significant coronary artery blockages.
  • In a trial involving 459 symptomatic patients, those with heart rates below 65 bpm showed better sensitivity using sequential CTCA compared to high-pitch spiral CTCA, though both methods had similar specificity and lower radiation doses for high-pitch protocols.
  • For patients with heart rates above 65 bpm, both sequential and retrospective CTCA showed comparable diagnostic performance, but sequential CTCA had a lower radiation dose overall, supporting its use for optimal accuracy with reduced exposure.
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Objectives: To investigate the diagnostic accuracy of CT coronary angiography (CTCA) in women at low to intermediate pre-test probability of coronary artery disease (CAD) compared with men.

Methods: In this retrospective study we included symptomatic patients with low to intermediate risk who underwent both invasive coronary angiography and CTCA. Exclusion criteria were previous revascularisation or myocardial infarction.

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Purpose: To compare image quality, radiation dose, and their relationship with heart rate of computed tomographic (CT) coronary angiographic scan protocols by using a 128-section dual-source CT scanner.

Materials And Methods: Institutional review board approved the study; all patients gave informed consent. Two hundred seventy-two patients (175 men, 97 women; mean ages, 58 and 59 years, respectively) referred for CT coronary angiography were categorized according to heart rate: less than 65 beats per minute (group A) and 65 beats per minute or greater (group B).

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Objective: To assess the influence of sex on the diagnostic performance of computed tomography coronary angiography (CTCA).

Methods: A total of 916 symptomatic patients (30.5% women) without earlier history of coronary artery intervention underwent both CTCA and invasive coronary angiography.

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