Juvenile myoclonic epilepsy is not associated with the DRPLA gene in a European population.

Background: Juvenile myoclonic epilepsy (JME), is an early-onset inherited generalized epilepsy which displays genetic heterogeneity, with at least 10 known loci. Another neurogenetic disease, dentato-rubro-pallido-luysian atrophy (DRPLA) presents three clinical phenotypes, one of which in Japanese displays many similarities to JME.

Aim: The purpose of this study was to investigate whether the DRPLA gene is associated with JME in Caucasians.

Neuropsychological EEG activation in patients with juvenile myoclonic epilepsy.

We studied the effects of higher mental activity on the EEG, i.e., neuropsychological EEG activation (NPA), in patients with juvenile myoclonic epilepsy (JME).