Publications by authors named "Stella Christou"
In the One Health context, wastewater treatment plants (WWTPs) are central to safeguarding water resources. Nonetheless, many questions remain about their effectiveness in preventing antimicrobial resistance (AMR) dissemination. Most surveillance studies monitor the levels and removal of selected antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs) in intracellular DNA (iDNA) extracted from WWTP influents and effluents.
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- Researchers analyzed hospital COVID-19 transmission using viral genomic and epidemiological data from 2181 patients and staff at a UK NHS Trust during two pandemic waves.
- Findings indicated a drop in staff-to-staff transmission from 31.6% to 12.9%, while patient-to-patient transmission surged from 27.1% to 52.1%.
- Control measures effectively curbed staff infections but failed to stop rising patient transmissions; thus, better detection of hospital-acquired cases is crucial to disrupt these transmission chains.
Amino acid metabolism is crucial for fungal growth and development. Ureohydrolases produce amines when acting on l-arginine, agmatine, and guanidinobutyrate (GB), and these enzymes generate ornithine (by arginase), putrescine (by agmatinase), or GABA (by 4-guanidinobutyrase or GBase). can metabolize and grow on arginine, agmatine, or guanidinobutyrate as the sole nitrogen source.
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