Publications by authors named "Steffen E Schnitzer"
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Synopsis of recent research by authors named "Steffen E Schnitzer"
- Steffen E Schnitzer's research prominently focuses on the impact of hypoxia on inflammatory processes and cancer cell behavior, highlighting the interaction between low oxygen levels and various biochemical pathways.
- His findings reveal that hypoxia can enhance the activity of sphingosine kinase 2, contributing to chemoresistance in lung cancer cells, thus indicating alternative survival mechanisms beyond the hypoxia-inducible factor (HIF-1) pathways.
- Schnitzer's work also investigates the regulation of HIF-1alpha under prolonged hypoxia, establishing the role of GSK3beta inhibition in restoring HIF-1alpha accumulation, which is crucial for understanding tumor response and survival under oxygen-depleted conditions.
