Submandibular gland involvement in oral cavity squamous cell carcinoma: a retrospective multicenter study.

Background: The submandibular gland (SMG) is routinely excised during neck dissection. Given the importance of the SMG in saliva production, it is important to understand its involvement rate by cancer tissue and the feasibility of its preservation.

Methods: Retrospective data were collected from five academic centers in Europe.

Oral cavity carcinoma in patients with and without a history of lichen planus: A comparative analysis.

Background: Oral potentially malignant disorders (OPMD) are associated with the risk of malignant transformation (MT) into oral cavity carcinoma (OCC). Oral lichen planus (OLP) is one of the most common OPMDs in western countries. Although there is a substantial amount of research on progression to cancer, a specific analysis of the clinical characteristics and prognosis of cancer developed in patients with a history of OLP versus patients without a history of OLP has not been investigated so far.