Publications by authors named "Stefano Passani"

Article Synopsis
  • The study investigates the impact of the number of involved structures (NIS) on the prognosis of patients with thymic epithelial tumors (TETs) who underwent surgery, using data from the European Society of Thoracic Surgeons (ESTS) thymic database.
  • Out of 303 patients analyzed, those with more than two involved structures had significantly worse cancer-specific survival (CSS) compared to those with two or fewer, with 5-year CSS rates of 9.5% versus 93.2%, respectively.
  • Factors such as neoadjuvant therapy, complete resection, and thymoma histology were associated with better prognosis, highlighting the importance of NIS in determining patient outcomes.
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Objectives: Compared to lung resections, airway procedures are relatively rare in thoracic surgery. Despite this, a growing number of dedicated airway centres have formed throughout Europe. These centres are characterized by a close interdisciplinary collaboration and they often act as supra-regional referring centres.

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Article Synopsis
  • The General Data Protection Regulation (GDPR), which came into effect in 2018 in the EU, has reshaped personal data management by imposing strict requirements on all entities handling data of EU residents, irrespective of their location.
  • It establishes core principles for data processing, including accuracy, transparency, and accountability, while also mandating the protection of sensitive data like health information and the appointment of Data Protection Officers.
  • The European Society of Thoracic Surgeons (ESTS) database exemplifies GDPR principles by ensuring secure data management and contributing to thoracic surgical research, but organizations must navigate compliance challenges to avoid penalties and uphold privacy rights.
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Objectives: We report an overview of surgical practices and outcomes in patients undergoing pulmonary metastasectomy based on data from the European Society of Thoracic Surgeons database.

Methods: We retrieved data on resections performed for pulmonary metastases between July 2007 and July 2019. We evaluated baseline characteristics, surgical management and postoperative outcomes.

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Objectives: We queried the European Society of Thoracic Surgeons (ESTS) prospective thymic database for descriptive analysis and for comparison with the ESTS retrospective thymic database (1990-2010).

Methods: Data were retrieved (January 2007-November 2017) for 1122 patients from 75 ESTS institutions.

Results: There were 484 (65%) thymomas, 207 (28%) thymic carcinomas and 49 (7%) neuroendocrine thymic tumours.

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Histological characteristics and clinical behaviour define lung neuroendocrine tumors (NETs), which are classified into four groups: typical (TC) and atypical carcinoids (AC), large-cell neuroendocrine carcinomas (LCNCs) and small-cell lung cancers (SCLCs). Historically, outcome and treatment of these rare neoplasms have been based on small, usually mono-institutional clinical series. Furthermore, their rarity makes quite impossible to design randomised clinical trial to compare different treatments especially in unusual clinical presentations.

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The European Society of Thoracic Surgeons (ESTS) thymic database is a satellite database of the ESTS registry collecting patients with thymic tumors (thymomas, thymic carcinomas and neuroendocrine thymic tumors) among the ESTS Institutions. The database is free of charge for any ESTS member, easily accessible to any ESTS institution, web-based, prospective, periodically maintained and updated. It may serve as an institutional database for the storage of data about patients with thymic tumors at no cost for each participating institution.

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