Publications by authors named "Stefano Cardelli"

Article Synopsis
  • The study wanted to see how surgery for inflammatory bowel disease (IBD) went when done with a robotic system versus traditional laparoscopy.
  • It looked at things like how long surgeries took, complications after surgery, and if patients had to stay longer in the hospital.
  • The results showed both methods were safe with similar outcomes, but the robotic surgeries took longer and had more internal connections made.
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Article Synopsis
  • In June 2023, a hospital started using a new robot system called Medtronic Hugo RAS for surgeries on the colon, aiming to improve how doctors perform these complex operations.
  • The study looked at 31 surgeries to see how well a new way of setting up the robot (called multi-docking) worked, especially how long it took to get the robot ready for surgery.
  • Results showed that with practice, doctors got faster at using the robot, reaching a good speed around the 15th surgery, which could help other doctors learning to use robot surgery too.
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Background: Concerns persist regarding the effectiveness of robotic proctectomy compared with open proctectomy for locally advanced rectal cancer with a high risk of circumferential resection margin involvement.

Objective: Comparison of surrogate cancer outcomes after robotic versus open proctectomy in this subpopulation.

Design: Retrospective cohort study.

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Article Synopsis
  • The study investigates postoperative complications following ileocaecal resection in patients with Crohn's Disease, specifically focusing on intra-abdominal septic complications (IASCs) and severe POCs.
  • Analysis of 853 patients revealed significant rates of complications, with lower preoperative albumin levels and a history of cardiovascular diseases being key predictors of severe POCs.
  • The findings suggest that oral budesonide is linked to a higher risk of IASCs, indicating the need for careful evaluation of this medication before surgery.
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Correct tumour restaging is pivotal for identifying the most personalised surgical treatment for patients with locally advanced rectal cancer undergoing neoadjuvant therapy, and works to avoid both poor oncological outcome and overtreatment. Digital rectal examination, endoscopy, and pelvic magnetic resonance imaging are the recommended modalities for local tumour restaging, while chest and abdominal computed tomography are utilised for the assessment of distant disease. The optimal length of time between neoadjuvant treatment and restaging, in terms of both oncological safety and clinical effectiveness of treatment, remains unclear, especially for patients receiving prolonged total neoadjuvant therapy.

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Article Synopsis
  • Locally Recurrent Rectal Cancer (LRRC) is a serious condition that can invade surrounding pelvic organs, making early diagnosis crucial for effective treatment.
  • The study used radiomic analysis to enhance imaging detection methods, specifically through CT and PET/CT scans, by evaluating quantitative tissue properties for better differentiation of LRRC.
  • Out of 563 patients, 57 suspected LRRC cases were analyzed, and specific radiomic features were identified that can significantly distinguish LRRC from non-LRRC cases, highlighting the importance of these techniques in improving diagnostic accuracy.
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