Publications by authors named "Stefanni Nonna M Paraguas"
Article Synopsis
- Spirometry is a test used to evaluate lung function by comparing it to normal levels in healthy non-smokers, focusing on metrics like forced vital capacity (FVC) and the FEV/FVC ratio.
- The study analyzed data from over 14,000 participants aged 40 and older across 41 sites, revealing regional differences in FVC tied to factors like age and height, categorized into four regions: Europe/richer countries, Near East, Africa, and Far East.
- Findings showed significant regional variations in FVC values between men and women, particularly in Europe compared to the Far East, but minimal differences in the FEV/FVC ratio across regions.
Background: Chronic airflow obstruction is a key characteristic of chronic obstructive pulmonary disease. We investigated whether isolated small airways obstruction is associated with chronic airflow obstruction later in life.
Methods: We used longitudinal data from 3957 participants of the multinational Burden of Obstructive Lung Disease study.
Background: Spirometric small airways obstruction (SAO) is common in the general population. Whether spirometric SAO is associated with respiratory symptoms, cardiometabolic diseases, and quality of life (QoL) is unknown.
Methods: Using data from the Burden of Obstructive Lung Disease study (N = 21,594), we defined spirometric SAO as the mean forced expiratory flow rate between 25 and 75% of the FVC (FEF) less than the lower limit of normal (LLN) or the forced expiratory volume in 3 s to FVC ratio (FEV/FVC) less than the LLN.
Background: Small airways obstruction is a common feature of obstructive lung diseases. Research is scarce on small airways obstruction, its global prevalence, and risk factors. We aimed to estimate the prevalence of small airways obstruction, examine the associated risk factors, and compare the findings for two different spirometry parameters.
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