In vitro characterization of PrismaLung+: a novel ECCOR device.

Background: Invasive mechanical ventilation is lifesaving in the setting of severe acute respiratory failure but can cause ventilation-induced lung injury. Advances in extracorporeal CO removal (ECCOR) technologies may facilitate more protective lung ventilation in acute respiratory distress syndrome, and enable earlier weaning and/or avoid invasive mechanical ventilation entirely in chronic obstructive pulmonary disease exacerbations. We evaluated the in vitro CO removal capacity of the novel PrismaLung+ ECCOR device compared with two existing gas exchangers.