Customized chitooligosaccharide production-controlling their length engineering of rhizobial chitin synthases and the choice of expression system.

Chitooligosaccharides (COS) have attracted attention from industry and academia in various fields due to their diverse bioactivities. However, their conventional chemical production is environmentally unfriendly and in addition, defined and pure molecules are both scarce and expensive. A promising alternative is the synthesis of desired COS in microbial platforms with specific chitin synthases enabling a more sustainable production.