Quality of life, disability, and clinical variables in amyotrophic lateral sclerosis.

Background: Amyotrophic lateral sclerosis (ALS) is a motor neuron disease that results in a progressive increase in dysfunctions, limitations and restrictions over time, which can impact on quality of life (QoL). Therefore, expanding knowledge on QoL and possible factors associated with ALS can enable the development of actions to ensure greater wellbeing for the population.

Objective: To investigate QoL in ALS and determine associations with demographic, functional and clinical aspects.